Martens Sabrina M, Nykamp Stephanie G, James Fiona M K
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1.
Can Vet J. 2018 Dec;59(12):1287-1292.
This retrospective cohort study reports the observation of magnetic resonance imaging (MRI) epaxial muscle hyperintensity in dogs diagnosed with presumptive fibrocartilaginous embolic myelopathy (FCEM) ( = 61). It further reports the observation of vertebral column hyperesthesia lasting > 12 hours. The hypothesis tested was that the finding of MRI epaxial muscle hyperintensity correlated with dogs presenting with hyperesthesia. Client-owned dogs diagnosed with presumptive FCEM by specific MRI criteria were included. Statistical analysis was performed using Fisher's exact test. Twenty-three percent (14/61) of MRIs displayed abnormal muscle hyperintensity and 43% (26/61) exhibited vertebral column hyperesthesia. No relationship was found between muscle hyperintensity and pain persisting beyond 12 hours. The muscle hyperintensity remains of unknown significance. That 43% of presumptive FCEM cases have prolonged signs of pain is a higher prevalence than previously reported, and may affect clinical differential diagnoses. This is especially significant in cases in which MRI is not possible and a presumptive diagnosis must be based on the clinical signs.
这项回顾性队列研究报告了对确诊为疑似纤维软骨栓塞性脊髓病(FCEM)(n = 61)的犬进行磁共振成像(MRI)检查时发现的轴上肌肉高信号。该研究还报告了持续超过12小时的脊柱感觉过敏的观察结果。所检验的假设是,MRI轴上肌肉高信号的发现与出现感觉过敏的犬有关。纳入了根据特定MRI标准被诊断为疑似FCEM的客户拥有的犬。使用Fisher精确检验进行统计分析。23%(14/61)的MRI显示肌肉高信号异常,43%(26/61)表现出脊柱感觉过敏。未发现肌肉高信号与持续超过12小时的疼痛之间存在关联。肌肉高信号的意义仍然不明。43%的疑似FCEM病例有延长的疼痛体征,这一患病率高于先前报道,可能会影响临床鉴别诊断。在无法进行MRI且必须根据临床体征做出疑似诊断的病例中,这一点尤为重要。