甲氨蝶呤诱发的脑室炎：常规放射性核素扫描及发射计算机断层扫描表现
Methotrexate-induced ventriculitis: appearance on routine radionculide scan and emission computed tomography.
作者信息
Makler P T, Gutowicz M F, Kuhl D E
出版信息
Clin Nucl Med. 1978 Jan;3(1):22-3. doi: 10.1097/00003072-197801000-00006.
Abstract
A 9-year-old boy with acute lymphocytic leukemia underwent intrathecal methotrexate (MTX) treatment over a period of one year because of CNS symptoms. After a sudden rapid deterioration, radionuclide imaging demonstrated marked ventricular wall concentration, presumed related to MTX toxicity. After cessation of MTX treatment, the patient improved, and subsequent radionuclide images reverted to normal appearance.
摘要
一名9岁急性淋巴细胞白血病男孩因中枢神经系统症状接受了为期一年的鞘内注射甲氨蝶呤（MTX）治疗。在病情突然迅速恶化后，放射性核素显像显示心室壁明显浓聚，推测与MTX毒性有关。停止MTX治疗后，患者病情好转，随后的放射性核素图像恢复正常。
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