Kurata Akira, Higaki Takashi, Yamamoto Eiichi, Shikata Fumiaki, Okamura Toru, Nagashima Mitsugi, Kido Tomoyuki, Kido Teruhito, Miyagawa Masao, Mochizuki Teruhito
Department of Diagnostic and Therapeutic Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon 791-0295, Japan.
Department of Pediatrics, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Japan.
J Cardiol Cases. 2011 Oct 2;5(1):e51-e54. doi: 10.1016/j.jccase.2011.09.004. eCollection 2012 Feb.
The mechanisms responsible for thromboembolic events in children with congenital heart disease have not yet been fully elucidated. Furthermore, establishment of long-term anticoagulation therapy in Fontan patients remains controversial. Here, we report the case of a 9-year-old boy who presented with hemiparesis due to a thromboembolic stroke; the boy had previously undergone staged pulmonary artery banding and Fontan procedure. Cardiac multidetector-row computed tomography (MDCT) clearly showed the supravalvular thrombus at the roofed (blind) pulmonary valve and circulatory stasis, which could be considered a possible source of the thrombus. Follow-up CT examination showed that the thrombus disappeared, but the circulatory stasis remained. Therefore, because the risk of thrombus formation was not eliminated, anticoagulation therapy was continued for the patient. Our case indicates the possible application of cardiac MDCT for providing insight into the hemodynamic mechanisms responsible for the thromboembolic events in children with congenital heart disease.
先天性心脏病患儿发生血栓栓塞事件的机制尚未完全阐明。此外,在Fontan手术患者中建立长期抗凝治疗仍存在争议。在此,我们报告一例9岁男孩,因血栓栓塞性中风出现偏瘫;该男孩此前接受了分期肺动脉环扎术和Fontan手术。心脏多排螺旋计算机断层扫描(MDCT)清楚地显示了在被覆盖(盲端)肺动脉瓣处的瓣上血栓和循环淤滞,这可被视为血栓的可能来源。随访CT检查显示血栓消失,但循环淤滞仍然存在。因此,由于血栓形成风险未消除,继续对该患者进行抗凝治疗。我们的病例表明,心脏MDCT可能有助于深入了解先天性心脏病患儿血栓栓塞事件的血流动力学机制。