Tagawa Minoru, Chinushi Masaomi, Nakamura Yuichi, Ochiai Yukie, Sato Akinori, Iijima Kenichi, Uchiyama Hiroko, Furushima Hiroshi, Aizawa Yoshifusa
Department of Cardiology, Nagaoka Chuo General Hospital, Niigata, Japan.
School of Health Science, Niigata University School of Medicine, Niigata, Japan.
J Cardiol Cases. 2012 May 17;6(1):e17-e19. doi: 10.1016/j.jccase.2012.03.008. eCollection 2012 Jul.
A healthy 25-year-old man suffered from loss of consciousness due to ventricular fibrillation (VF). Emergency services required multiple cardioversion to restore sinus rhythm. Repeated electrocardiographic (ECG) recordings after admission showed non-type 1 Brugada ST-segment elevation in V1 and V2. Intravenous pilsicainide infusion augmented the ST-segment elevation but its morphology did not represent type-1 ECG. Intravenous administration of isoproterenol normalized the ST-segment elevation, and programmed electrical stimulation induced VF. Spontaneous VF recurred 1 year after introduction of implantable cardioverter defibrillator. Non-type 1 ST-segment elevation, to which pharmacological responses are similar to Brugada syndrome, may be used as a hallmark of ventricular tachyarrhythmia.
一名25岁健康男性因室颤(VF)而意识丧失。急救人员进行了多次心脏复律以恢复窦性心律。入院后反复的心电图(ECG)记录显示V1和V2导联有非1型Brugada综合征的ST段抬高。静脉输注吡西卡尼使ST段抬高加重,但其形态并不代表1型心电图。静脉注射异丙肾上腺素使ST段抬高恢复正常,程序电刺激诱发了室颤。植入式心脏复律除颤器植入1年后室颤自发复发。非1型ST段抬高,其药理学反应与Brugada综合征相似,可作为室性快速心律失常的一个标志。