Busch Anne, Elschner Mandy Carolina, Jacob Daniela, Grunow Roland, Tomaso Herbert
Friedrich-Loeffler-Institut, Institute of Bacterial Infections and Zoonoses, Jena, Germany.
Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Highly Pathogenic Microorganisms (ZBS 2), Berlin, Germany.
Microbiol Resour Announc. 2018 Oct 11;7(14). doi: 10.1128/MRA.00972-18. eCollection 2018 Oct.
A Bacillus anthracis vaccine strain (Sterne), used as an attenuated laboratory comparative strain, was sequenced and analyzed. A comparison to assemblies of B. anthracis strain Sterne (NZ_CP009541 and NZ_CP009540) was performed. The lack of the pX02 plasmid and pX01 in approximately five copies was confirmed.
对用作减毒实验室对照菌株的炭疽芽孢杆菌疫苗株(Sterne株)进行了测序和分析。与炭疽芽孢杆菌Sterne株(NZ_CP009541和NZ_CP009540)的组装序列进行了比较。证实该菌株缺失pX02质粒且pX01质粒约缺失五个拷贝。