在人类同种异体移植受者中诱导对抗淋巴细胞球蛋白无反应性。
Induction in human allograft recipients of unresponsiveness to anti-lymphocyte globulin.
作者信息
Martin C A, Condie R M, Esquenazi V, Anthone R, Anthone S, Milgrom F
机构信息
Department of Microbiology, School of Medicine, State University of New York, Buffalo 14214.
出版信息
Immunol Invest. 1988 Jun;17(4):265-72. doi: 10.3109/08820138809041416.
The observations presented here confirm previous reports that polyclonal ALG prepared at the University of Minnesota or ATGAM of The Upjohn Co., administered as described, rarely induced sensitization of patients to the horse gamma globulin. In addition, the phenomena of transient antibody production prior to the onset of unresponsiveness and the induction of unresponsiveness in individuals with preexisting antibodies were observed.
此处呈现的观察结果证实了之前的报告，即按照所述方法给药的明尼苏达大学制备的多克隆抗淋巴细胞球蛋白（ALG）或Upjohn公司的抗胸腺细胞球蛋白（ATGAM），很少会使患者对马γ球蛋白产生致敏。此外，还观察到在无反应性开始之前短暂抗体产生的现象，以及在已有抗体的个体中诱导出无反应性的现象。
Zotero 插件