医学实习生对抗微生物药物耐药性的态度和看法：埃塞俄比亚多中心横断面研究。
Attitude and perception of medical interns about antimicrobial resistance: a multi center cross-sectional study in Ethiopia.
机构信息
School of Medicine, College of Medicine and Health Sciences, University of Gondar, P.O. Box: 196, Gondar, Ethiopia.
出版信息
Antimicrob Resist Infect Control. 2018 Dec 4;7:149. doi: 10.1186/s13756-018-0443-9. eCollection 2018.
BACKGROUND
Antibiotic resistance is a global burden and reduction of antimicrobial resistance requires change in antimicrobial prescribing behavior of health workers. The current study aimed to evaluate the attitude and perception of Ethiopian medical interns towards antimicrobials resistance.
METHODS
A multi center cross-sectional institutional based survey was conducted from August 2016 to October 2016 among medical interns in Ethiopia. Data entered and analyzed using Statistical Package for Social Sciences program (SPSS) software version 21.0 for Windows. Descriptive statistics, chi-square test and binary logistic regression analysis were used and statistical significance was set at < 0.05 as a cut of point.
RESULTS
Out of the 278 questionnaires distributed, 270 were returned completed giving a response rate of 97.1%. Most of the participants 256 (94.8%) wants to receive further education about antimicrobial stewardship. Chi-square test showed a significant difference between institutions about interns' attitude and perception concerning over usage of antimicrobials in their institutions; description of correct antimicrobial coverage; handling patients who demands antimicrobial therapy that is not indicated and finding reliable sources of information to treat infections ( < 0.05). Attaching at internal medicine wards during the survey and receiving antimicrobial stewardship training during the past 6 months were found to improve their attitude significantly by 2.68 and 3.48 times respectively.
CONCLUSIONS
The current study demonstrates an enormous desire of medical interns for further education about antimicrobial stewardship. Hence, it is strongly recommended to provide a comprehensive, regular, standard and up to date educational training in all medical institutions for our future prescribers. Medical institutions and stakeholders are recommended to advocate curriculums and policies that build up antimicrobial stewardship programs.
背景
抗生素耐药性是一个全球性的负担，减少抗菌药物耐药性需要改变卫生工作者的抗菌药物处方行为。本研究旨在评估埃塞俄比亚实习医生对抗菌药物耐药性的态度和看法。
方法
2016 年 8 月至 10 月，在埃塞俄比亚的医疗机构中，对实习医生进行了一项多中心横断面机构基础调查。使用统计软件包（SPSS）软件版本 21.0 for Windows 输入和分析数据。使用描述性统计、卡方检验和二元逻辑回归分析，以 < 0.05 作为统计显著性的截止点。
结果
在发放的 278 份问卷中，有 270 份回收完成，应答率为 97.1%。大多数参与者 256 人（94.8%）希望接受更多关于抗菌药物管理的继续教育。卡方检验显示，机构之间在实习医生对其机构中过度使用抗菌药物的态度和看法、正确的抗菌药物覆盖范围的描述、处理要求使用未指明的抗菌药物治疗的患者以及寻找可靠的信息来源来治疗感染方面存在显著差异；（<0.05）。在调查期间被分配到内科病房和在过去 6 个月内接受抗菌药物管理培训被发现分别显著提高了他们的态度 2.68 倍和 3.48 倍。
结论
本研究表明，实习医生对抗菌药物管理继续教育有着巨大的渴望。因此，强烈建议在所有医疗机构中提供全面、定期、标准和最新的教育培训，为我们未来的处方者提供服务。医疗机构和利益相关者被建议倡导建立抗菌药物管理计划的课程和政策。
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