用于评估小鼠总体健康状况的筑巢试验
The Nest Building Test in Mice for Assessment of General Well-Being.
作者信息
Kraeuter Ann-Katrin, Guest Paul C, Sarnyai Zoltán
机构信息
Laboratory of Psychiatric Neuroscience, Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, QLD, Australia.
Discipline of Biomedicine, College of Public Health, Medicine and Veterinary Sciences, James Cook University, Townsville, QLD, Australia.
出版信息
Methods Mol Biol. 2019;1916:87-91. doi: 10.1007/978-1-4939-8994-2_7.
This chapter presents a method for assessing general behavior, well-being, and sensorimotor gating. A detailed protocol is given for assessment of nest building performance in female mice using a strict scoring system. The test can be used for assessing moods and behaviors associated with psychiatric disorders such as depression and schizophrenia. It can also be useful for testing movement disorders such as Parkinson disease.
本章介绍了一种评估一般行为、健康状况和感觉运动门控的方法。给出了一个详细的方案，用于使用严格的评分系统评估雌性小鼠的筑巢性能。该测试可用于评估与抑郁症和精神分裂症等精神疾病相关的情绪和行为。它也可用于测试帕金森病等运动障碍。
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