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法国全国 ELFE 队列中幼儿铁强化配方的使用与社会经济因素的关联。

Iron-fortified formula use in young children and association with socioeconomic factors in the French nationwide ELFE cohort.

机构信息

Centre of Research in Epidemiology and Statistics Sorbonne Paris Cité, Obstetrical, Perinatal and Pediatric Epidemiology Research team (EPOPé), Labex GR-Ex, Inserm, UMR1153, Paris, France.

Department of General Pediatrics and Pediatric Infectious Diseases, Necker-Enfants malades Hospital AP-HP, Paris, France.

出版信息

Acta Paediatr. 2019 Jul;108(7):1285-1294. doi: 10.1111/apa.14682. Epub 2019 Jan 24.

Abstract

AIM

To study the rate of iron-fortified infant formula (IFF) use in young children in France and its association with socioeconomic factors.

METHODS

The ELFE national birth cohort included, in 2011, 18 329 living births in 349 hospitals randomly selected. The present analyses were restricted to children with follow-up at age two years. Milk consumption was evaluated by parental telephone interview, and its association with socioeconomic factors was studied.

RESULTS

The 12 341 analysed children had a mean age of 26 months; 50% were girls. Rate of IFF use before two years old and at two years old was 65% and 43%, respectively. At age two years, use of IFF was lower with young age of the mother (adjusted OR [aOR] = 0.4, 95% CI: 0.3-0.5), low educational level (aOR = 0.7, 95% CI: 0.6-0.9), high parity (aOR = 0.3, 95% CI 0.2-0.4), and mother smoking (aOR = 0.8, 95% CI: 0.7-0.9) as well as low household income (aOR = 0.5, 95% CI: 0.4-0.7), and parents' unemployment (aOR = 0.7, 95% CI: 0.5-0.9).

CONCLUSION

In this national population-based study, the rate of implementation of the ID prevention strategy was much lower at two years old than before two years old, and significantly lower in disadvantaged populations.

摘要

目的

研究法国幼儿铁强化配方奶粉(IFF)的使用率及其与社会经济因素的关系。

方法

ELFE 全国出生队列纳入了 2011 年在 349 家随机选择的医院中出生的 18329 名活产儿。本分析仅限于在 2 岁时进行随访的儿童。通过父母电话访谈评估牛奶的摄入量,并研究其与社会经济因素的关系。

结果

12341 名分析儿童的平均年龄为 26 个月;50%为女孩。在 2 岁之前和 2 岁时,IFF 的使用率分别为 65%和 43%。在 2 岁时,母亲年龄较小(调整后的比值比[aOR] = 0.4,95%CI:0.3-0.5)、教育水平较低(aOR = 0.7,95%CI:0.6-0.9)、多胎产(aOR = 0.3,95%CI 0.2-0.4)、母亲吸烟(aOR = 0.8,95%CI:0.7-0.9)以及家庭收入较低(aOR = 0.5,95%CI:0.4-0.7)、父母失业(aOR = 0.7,95%CI:0.5-0.9)时,使用 IFF 的可能性较低。

结论

在这项基于全国人口的研究中,2 岁时预防缺铁性贫血策略的实施率明显低于 2 岁之前,且在弱势群体中明显较低。

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