Ahmid M, Ahmed S F, Shaikh M G
Development Endocrinology Research Group, School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK,
Ther Clin Risk Manag. 2018 Nov 23;14:2283-2291. doi: 10.2147/TCRM.S136576. eCollection 2018.
Childhood-onset growth hormone deficiency (CO-GHD) is an endocrine condition associated with a broad range of health issues from childhood through to adulthood, which requires particular attention during the transition period from adolescence to young adulthood. There is uncertainty in the clinical practice of the management of CO-GHD during transition regarding the clinical assessment and management of individual patients during and after transition to obtain optimal follow-up and improved health outcomes. Despite the availability of clinical guidelines providing the framework for transition of young adults with CO-GHD, there remains substantial variation in approaching transitional care among pediatric and adult services. A well-structured and coordinated transitional plan with clear communication and direct collaboration between pediatric and adult health care to ensure optimal management of adolescents with CO-GHD during transition is needed.
儿童期起病的生长激素缺乏症（CO-GHD）是一种内分泌疾病，与从儿童期到成年期的一系列广泛健康问题相关，在从青春期到青年期的过渡阶段需要特别关注。在过渡期间CO-GHD的管理临床实践中，对于过渡期间及之后个体患者的临床评估和管理，以获得最佳随访和改善健康结果方面存在不确定性。尽管有临床指南为患有CO-GHD的年轻人的过渡提供框架，但儿科和成人服务机构在提供过渡性护理的方式上仍存在很大差异。需要一个结构完善且协调的过渡计划，在儿科和成人医疗保健之间进行清晰的沟通和直接协作，以确保患有CO-GHD的青少年在过渡期间得到最佳管理。
