Peralta Sonia Luque, Dutra André Lindemann, Leles Sávio Bisinoto de, Ribeiro Juliana Silva, Ogliari Fabricio Aulo, Piva Evandro, Lund Rafael Guerra
Faculdade Metropolitana da Grande Fortaleza, Programa de Graduação em Odontologia, Fortaleza, Ceará, Brasil.
Universidade Federal de Pelotas, Faculdade de Odontologia, Programa de Pós-Graduação em Odontologia (PPGO), Pelotas, Rio Grande do Sul, Brasil.
J Appl Oral Sci. 2018 Dec 10;27:e20180183. doi: 10.1590/1678-7757-2018-0183.
This study investigated the physical and mechanical properties, antibacterial effect and biocompatibility of novel elastomeric temporary resin-based filling materials (TFMs) containing zinc methacrylate (ZM).
Experimental TFMs were prepared by mixing the zinc methacrylate with monomer, co-monomer, photoinitiator and fillers. A ZM concentration of 0 (control), 0.5% (Z0.5); 1% (Z1), 2% (Z2), or 5% (ZM5) wt% was added to the TFMs. Fermit-N (F) was used for comparison with the experimental material. Microleakage, water sorption/solubility, degree of conversion, depth of cure, ultimate tensile strength, and hardness were determined and compared. A modified direct contact test (DCT) with Enterococcus faecalis and a Streptococcus mutans' biofilm accumulation assay was carried out to evaluate the antimicrobial effect and cytotoxicity of the assay. Statistical comparisons were performed (α=5%).
The results showed that the physical and mechanical properties of the experimental TFMs with ZM are comparable with the properties of the commercial reference and some properties were improved, such as lower microleakage and water sorption, and higher ultimate tensile strength values. TFMs with ZM killed E. faecalis only after 1 h. Biofilm development of S. mutans was not affected by the inclusion of ZM in the experimental TFMs.
The present findings suggest that the physical, mechanical and biological properties of the experimental TFMs with ZM are comparable with the properties of the commercial reference. However, some properties were improved, such as lower microleakage and water sorption, and higher ultimate tensile strength values.
本研究调查了含甲基丙烯酸锌(ZM)的新型弹性体临时树脂基充填材料(TFM)的物理和机械性能、抗菌效果及生物相容性。
通过将甲基丙烯酸锌与单体、共聚单体、光引发剂和填料混合制备实验性TFM。在TFM中添加0(对照)、0.5%(Z0.5)、1%(Z1)、2%(Z2)或5%(ZM5)重量百分比的ZM。使用Fermit-N(F)与实验材料进行比较。测定并比较微渗漏、吸水率/溶解度、转化率、固化深度、极限拉伸强度和硬度。采用改良的粪肠球菌直接接触试验(DCT)和变形链球菌生物膜积聚试验来评估抗菌效果和细胞毒性。进行统计学比较(α=5%)。
结果表明,含ZM的实验性TFM的物理和机械性能与商业对照品相当,且一些性能得到了改善,如更低的微渗漏和吸水率,以及更高的极限拉伸强度值。含ZM的TFM仅在1小时后杀死粪肠球菌。实验性TFM中加入ZM对变形链球菌生物膜的形成没有影响。
目前的研究结果表明,含ZM的实验性TFM的物理、机械和生物学性能与商业对照品相当。然而,一些性能得到了改善,如更低的微渗漏和吸水率,以及更高的极限拉伸强度值。