接受袖状胃切除术和Roux-en-Y胃旁路术患者的血脂谱分析。

Analysis of the lipid profile of patients submitted to sleeve gastrectomy and Roux-en-Y gastric bypass.

作者信息

Lira Natália S, Macedo Carlos Eduardo Soares, Belo Giselle Menezes, Santa-Cruz Fernando, Siqueira Luciana T, Ferraz Álvaro Antonio Bandeira

机构信息

Universidade Federal de Pernambuco, Programa de Pós-Graduação em Cirurgia, Recife, PE, Brasil.

Universidade Federal de Pernambuco, Curso de Medicina, Recife, PE, Brasil.

出版信息

Rev Col Bras Cir. 2018 Dec 10;45(6):e1967. doi: 10.1590/0100-6991e-20181967.

DOI:10.1590/0100-6991e-20181967

PMID:30540098

Abstract

OBJECTIVE

to compare the improvements in lipid profile in patients undergoing sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB).

METHODS

in a mixed cohort study, we evaluated 334 patients undergoing SG and 178 patients undergoing RYGB at the University Hospital of the Federal University of Pernambuco and at the Real Hospital Português de Beneficência, Recife, PE, Brazil. We measured serum levels of total cholesterol, LDL, HDL and triglycerides preoperatively and at three, six, 12 and 24 months follow-up.

RESULTS

the SG group consisted of 58 men and 276 women. In the group submitted to RYGB, there were 64 men and 114 women. The mean age was 37.2±20.5 years in the SG group and 41.9±11.1 years in the RYGB group. The preoperative mean BMI was 39.4±2.6kg/m2 and 42.7±5.8kg/m2 for the SG and RYGB groups, respectively. In the preoperative period, 80% of the patients had at least one abnormality in the lipid profile. Two years after surgery, there was improvement in total cholesterol, LDL, HDL and triglycerides in the group submitted to RYGB. In the group submitted to SG, after two years there was improvement in total cholesterol, HDL and triglyceride levels.

CONCLUSION

both techniques resulted in improvements in the lipid profile, but the RYGB was more effective.

摘要

目的

比较接受袖状胃切除术（SG）和Roux-en-Y胃旁路术（RYGB）的患者血脂水平的改善情况。

方法

在一项混合队列研究中，我们评估了巴西伯南布哥联邦大学大学医院和累西腓葡萄牙慈善医院的334例接受SG的患者和178例接受RYGB的患者。我们在术前以及术后3个月、6个月、12个月和24个月随访时测量了血清总胆固醇、低密度脂蛋白、高密度脂蛋白和甘油三酯水平。

结果

SG组包括58名男性和276名女性。接受RYGB的组中有64名男性和114名女性。SG组的平均年龄为37.2±20.5岁，RYGB组为41.9±11.1岁。SG组和RYGB组术前平均体重指数分别为39.4±2.6kg/m²和42.7±5.8kg/m²。术前，80%的患者血脂水平至少有一项异常。手术后两年，接受RYGB的组中总胆固醇、低密度脂蛋白、高密度脂蛋白和甘油三酯均有改善。接受SG的组在两年后总胆固醇、高密度脂蛋白和甘油三酯水平有所改善。