Universidade Federal de Pernambuco - Recife (PE), Brazil.
Universidade Federal de Alagoas - Maceió (AL), Brazil.
Arq Bras Cir Dig. 2023 Jul 28;36:e1753. doi: 10.1590/0102-672020230035e1753. eCollection 2023.
Vitamin, mineral, and metabolic deficiencies occur in the postoperative period of bariatric surgery, in the short and long term, and are worrisome intercurrences.
To evaluate the association of serum vitamin D levels with the lipid profile in obese patients undergoing bariatric surgery.
Case series of patients assisted from 2010 to 2018, in a private hospital of medium and high complexity, who underwent bariatric surgery using sleeve gastrectomy or Roux-en-Y gastric bypass techniques, monitored by the same surgeon. Sociodemographic, clinical, laboratory, and anthropometric data were collected preoperatively and at 6, 12, and 24 months after surgery.
A total of 156 individuals, mostly female (75.6%) were monitored. The most frequent comorbidities were hepatic steatosis (76.3%) and hypertension (48.27). Regarding preoperative vitamin D levels, only 18.9% of the population had a satisfactory level (≥30 ng/mL). There was a reduction in weight and an improvement in the lipid profile after surgery. Significant correlations were observed between the lipid profile and vitamin D concentration only in the sample submitted to the Roux-en-Y gastric bypass technique: negative correlation between total cholesterol and vitamin D two years after surgery; positive correlation between triglycerides and vitamin D one year after surgery; and negative correlation between high-density lipoprotein and vitamin D two years post-surgery.
It is essential to routinely monitor vitamin D levels and lipid profile pre- and postoperatively in order to avoid damage associated with this vitamin deficiency.
在减重手术的术后短期和长期,都会出现维生素、矿物质和代谢缺陷,这是令人担忧的并发症。
评估肥胖患者接受减重手术后血清维生素 D 水平与血脂谱的相关性。
这是一项 2010 年至 2018 年期间在一家中高复杂度的私立医院接受袖状胃切除术或 Roux-en-Y 胃旁路手术的患者的病例系列研究,这些患者由同一位外科医生进行监测。收集术前以及术后 6、12 和 24 个月的社会人口统计学、临床、实验室和人体测量数据。
共监测了 156 名个体,其中大多数为女性(75.6%)。最常见的合并症是肝脂肪变性(76.3%)和高血压(48.27%)。关于术前维生素 D 水平,只有 18.9%的人群有一个满意的水平(≥30ng/mL)。手术后体重减轻,血脂谱改善。仅在接受 Roux-en-Y 胃旁路手术的样本中观察到血脂谱与维生素 D 浓度之间存在显著相关性:总胆固醇与手术后两年的维生素 D 呈负相关;手术后一年甘油三酯与维生素 D 呈正相关;高密度脂蛋白与手术后两年的维生素 D 呈负相关。
为了避免与这种维生素缺乏相关的损害,有必要在术前和术后常规监测维生素 D 水平和血脂谱。