Sturman J A
Department of Developmental Biochemistry, Institute for Basic Research in Developmental Disabilities, Staten Island, NY 10314.
J Nutr. 1988 Oct;118(10):1169-76. doi: 10.1093/jn/118.10.1169.
Taurine is a ubiquitous dietary constituent of most mammals and is present in especially high concentrations in the tissues of developing mammals. Research to date indicates that taurine plays an important role in the development of the nervous system and the process of migration in particular. It is speculated that taurine uptake and release, in conjunction with glutamate uptake and release, may represent one form of communication between neurons and glial cells. The need of taurine by the body is emphasized by the ability of the kidney to curtail taurine excretion to conserve taurine in the face of a low dietary taurine intake. The evidence for a special role of taurine in development is considered and discussed.
牛磺酸是大多数哺乳动物饮食中普遍存在的成分，在发育中的哺乳动物组织中含量尤其高。迄今为止的研究表明，牛磺酸在神经系统发育中，尤其是在迁移过程中起着重要作用。据推测，牛磺酸的摄取和释放，与谷氨酸的摄取和释放一起，可能代表了神经元与神经胶质细胞之间的一种通讯形式。面对低饮食牛磺酸摄入量时，肾脏减少牛磺酸排泄以保存牛磺酸的能力强调了身体对牛磺酸的需求。本文对牛磺酸在发育中特殊作用的证据进行了考量和讨论。
