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产后出血严重管理的差异:一项基于国家虚拟病例的研究。

Variation in severe postpartum hemorrhage management: A national vignette-based study.

机构信息

Department of Obstetrics and Gynecology, Poissy-Saint Germain Hospital, Poissy, France.

INSERM U1153, METHODS (Méthodes en Évaluation Thérapeutique des Maladies Chroniques) Research Unit. Paris Descartes-Sorbonne Paris Cité University, Paris, France.

出版信息

PLoS One. 2018 Dec 13;13(12):e0209074. doi: 10.1371/journal.pone.0209074. eCollection 2018.

Abstract

OBJECTIVES

To assess variations in management of severe postpartum hemorrhage: 1) between obstetricians in the same situation 2) by the same obstetrician in different situations.

STUDY DESIGN

A link to a vignette-based survey was emailed to obstetricians of 215 maternity units; the questionnaire asked them to report how they would manage the PPH described in 2 previously validated case-vignettes of different scenarios of severe PPH. Vignette 1 described a typical immediate, severe PPH, and vignette 2 a less typical case of severe but gradual PPH. They were constructed in 3 successive steps and included multiple-choice questions proposing several types of clinical practice options at each step. Variations in PPH were assessed in a descriptive analysis; agreement about management and its timing between vignette 1 and vignette 2 was assessed with the Kappa coefficient.

RESULTS

Analysis of complete responses from 119 (43.4%) obstetricians from 53 (24.6%) maternity units showed delayed or inadequate management in both vignettes. While 82.3% and 83.2% of obstetricians (in vignettes 1 and 2, respectively) would administer oxytocin 15 minutes after PPH diagnosis, only 52.9% and 29.4% would alert other team members. Management by obstetricians of the two vignette situations was inconsistent in terms of choice of treatment and timing of almost all treatments.

CONCLUSION

Case vignettes demonstrated inadequate management as well as variations in management between obstetricians and in different PPH situations. Protocols or procedures are necessary in all maternity units to reduce the variations in practices that may explain a part of the delay in management that leads to PPH-related maternal mortality and morbidity.

摘要

目的

评估严重产后出血管理的变化:1)在同一情况下的产科医生之间,2)在不同情况下的同一产科医生之间。

研究设计

向 215 个产科单位的产科医生发送了一份基于病例描述的调查链接;问卷要求他们报告如何管理 2 个先前验证过的严重产后出血病例描述中的 PPH,这两个病例描述了不同严重产后出血情况下的不同场景。病例 1 描述了一种典型的立即、严重的 PPH,病例 2 描述了一种不太典型但逐渐加重的严重 PPH。这两个病例是分三个步骤构建的,每个步骤都包含多项选择题,提出了几种类型的临床实践选择。对 PPH 的变化进行了描述性分析;使用 Kappa 系数评估病例 1 和病例 2 之间管理及其时间的一致性。

结果

对来自 53 个产科单位的 119 名(43.4%)产科医生的完整回复进行分析显示,在两个病例中都存在延迟或不充分的管理。虽然 82.3%和 83.2%的产科医生(分别在病例 1 和病例 2 中)会在 PPH 诊断后 15 分钟内给予催产素,但只有 52.9%和 29.4%会通知其他团队成员。根据治疗选择和几乎所有治疗的时间,两位产科医生对这两个病例描述情况的管理不一致。

结论

病例描述显示了管理不足以及产科医生之间以及不同 PPH 情况下管理的变化。所有产科单位都需要制定协议或程序,以减少实践中的变化,这可能解释了管理延迟的一部分,导致与 PPH 相关的产妇死亡和发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf30/6292622/8e943dcc27f1/pone.0209074.g001.jpg

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