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[因出血导致的孕产妇死亡:法国2010 - 2012年孕产妇死亡机密调查结果]

[Maternal deaths due to haemorrhage: Results from the French confidential enquiry into maternal deaths, 2010-2012].

作者信息

Morau E, Ducloy J C, Le Roux S, Weber P, Dreyfus M

机构信息

Service d'anesthésie-réanimation, pôle mère-enfant, CHU de Montpellier, 191, avenue du Doyen-Gaston-Giraud, 34000 Montpellier, France.

Maternité hôpital privé de Villeneuve-d'Ascq, quartier du recueil, 20, avenue de La Reconnaissance, 59491 Villeneuve-d'Ascq, France.

出版信息

Gynecol Obstet Fertil Senol. 2017 Dec;45(12S):S24-S30. doi: 10.1016/j.gofs.2017.10.012. Epub 2017 Nov 10.

Abstract

Haemorrhage is the first cause of maternal mortality and morbidity in France and a quality of care marker. Haemorrhage rate in France is around 5 to 10% of deliveries. PPH is defined as a post-partum blood loss≥500mL whatever the delivery route and sometime blood can be concealed inside the pelvis. Between 2010 and 2012 in France, 29 deaths were related to haemorrhage giving a maternal mortality ratio of 1.2/100,000 live births (CI 95% 0.8-1.7). Haemorrhage cases decreased from last triennium (2007-2009) especially for uterine atony cases (12/29) but remains the first leading cause of direct maternal death. Patients with previous cesarean birth were more represented than in general obstetrical population (11/23). Substandard care were mainly due to delays in diagnosis of hemoperitoneum, delays in adequate resuscitation because of reassuring vital signs (normal blood pressure or normal hematocrite at the initial stage of bleeding) or organisational mistakes.

摘要

在法国,出血是孕产妇死亡和发病的首要原因,也是医疗质量的一个指标。法国的出血发生率约为分娩总数的5%至10%。产后出血(PPH)定义为无论分娩方式如何,产后失血量≥500mL,有时血液可能隐匿于盆腔内。2010年至2012年期间,法国有29例死亡与出血有关,孕产妇死亡率为1.2/10万活产(95%置信区间0.8 - 1.7)。与上一个三年期(2007 - 2009年)相比,出血病例有所减少,尤其是宫缩乏力病例(12/29),但出血仍是孕产妇直接死亡的首要原因。有剖宫产史的患者在出血病例中的占比高于普通产科人群(11/23)。护理不达标主要归因于腹腔积血诊断延误、因生命体征稳定(出血初始阶段血压正常或血细胞比容正常)导致的充分复苏延误或组织失误。

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