Suppr超能文献

[睾丸髓系肉瘤]

[Myeloid Sarcoma of the Testis].

作者信息

Yoshida Kenta, Uemura Koichi, Inoue Masahiro, Mizuno Nobuhiko, Murakami Takayuki, Tsuchiya Futoshi

机构信息

The Department of Urology, Yokohama City Minato Red Cross Hospital.

出版信息

Hinyokika Kiyo. 2018 Nov;64(11):459-463. doi: 10.14989/ActaUrolJap_64_11_459.

Abstract

A 68-year-old man with swelling of his left testis was referred to our hospital. There was no history of hematologic disease. The diameter of the testicular mass was 40 mm. We performed a left orchiectomy. Histopathologic examination revealed diffuse infiltration of immature neoplastic cells with a high nuclearcytoplasmic ratio. Immunohistochemical analysis revealed that cells were positive for myeloperoxidase, while T-cell and B-cell markers were negative. There was no evidence of leukemia cells in peripheral blood or in bone marrow. The tumor was diagnosed as a testicular isolated myeloid sarcoma. Eleven months after the orchiectomy, enlargement of the para-aortic lymph node occurred. There was no evidence of leukemia cells in the peripheral blood or bone marrow. The patient is undergoing chemotherapy for recurrence of myeloid sarcoma. Myeloid sarcoma is an extramedullary tumor composed of immature myeloid cells. Myeloid sarcoma primarily involving the testis is rare. However, it is important to consider it as a differential diagnosis because it has a poor prognosis.

摘要

一名68岁左侧睾丸肿大的男性被转诊至我院。他无血液系统疾病史。睾丸肿块直径为40毫米。我们实施了左侧睾丸切除术。组织病理学检查显示未成熟肿瘤细胞弥漫浸润,核质比高。免疫组织化学分析显示细胞髓过氧化物酶呈阳性,而T细胞和B细胞标志物呈阴性。外周血和骨髓中均无白血病细胞证据。该肿瘤被诊断为睾丸孤立性髓系肉瘤。睾丸切除术后11个月,腹主动脉旁淋巴结肿大。外周血和骨髓中均无白血病细胞证据。该患者正在接受针对髓系肉瘤复发的化疗。髓系肉瘤是一种由未成熟髓样细胞组成的髓外肿瘤。主要累及睾丸的髓系肉瘤很罕见。然而,将其作为鉴别诊断很重要,因为其预后较差。

相似文献

1
[Myeloid Sarcoma of the Testis].[睾丸髓系肉瘤]
Hinyokika Kiyo. 2018 Nov;64(11):459-463. doi: 10.14989/ActaUrolJap_64_11_459.
2
Granulocytic sarcoma of the testis.睾丸粒细胞肉瘤
Urology. 2004 Mar;63(3):584-5. doi: 10.1016/j.urology.2003.10.059.
8
Myeloid sarcoma involving the testis.累及睾丸的髓系肉瘤。
Am J Clin Pathol. 2005 Sep;124(3):445-52. doi: 10.1309/NXLC-J1B1-6YDF-QWND.
9
Testicular chloroma in a nonleukemic infant.
J Pediatr Hematol Oncol. 2005 Jul;27(7):393-6. doi: 10.1097/01.mph.0000173847.87539.e0.
10
Testicular granulocytic sarcoma without systemic leukemia.
Urol Int. 2005;75(1):94-6. doi: 10.1159/000085937.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验