Imshenetskiĭ A A, Nesterova N G, Cherkesova G V, Fetisova Z S
Mikrobiologiia. 1988 May-Jun;57(3):394-7.
The effect of some inhibitors and bivalent metal cations (Mn2+, Ca2+, Fe2+, Zn2+, Mg2+, Co2+ and Cu2+) on the proteolytic activity of two Bacillus mesentericus strains (strain 8 and strain 64 M-variant) was comparatively studied. The both enzymes were shown to be serine proteinases, but the proteinase of strain 64 was also a metal-dependent enzyme. Metal ions exerted no essential effect on the proteinase of strain 8. Ca2+ and Mg2+ ions stimulated the proteinase activity of strain 64 whereas Fe2+ and Zn2+ ions inhibited it in the case of three substrates. Therefore, the two proteinases are different.
比较研究了一些抑制剂和二价金属阳离子（Mn2+、Ca2+、Fe2+、Zn2+、Mg2+、Co2+和Cu2+）对两株肠系膜芽孢杆菌（8号菌株和64 M-变体菌株）蛋白水解活性的影响。结果表明，这两种酶均为丝氨酸蛋白酶，但64号菌株的蛋白酶也是一种金属依赖性酶。金属离子对8号菌株的蛋白酶没有显著影响。Ca2+和Mg2+离子刺激了64号菌株的蛋白酶活性，而在三种底物的情况下，Fe2+和Zn2+离子抑制了该活性。因此，这两种蛋白酶是不同的。
