Litvinovich S V, Medved' L V
Mol Biol (Mosk). 1988 Jul-Aug;22(4):934-43.
A detailed analysis of further proteolytic degradation of fibrinogen fragment DH (Mr 95 kDa) was performed. Two new proteolytic fragments DLA and DL derived from DH-fragment have been purified and analyzed. The results obtained allow to propose a general scheme of DH-fragment proteolysis by stepwise splitting of their individual domains. The borders and molecular masses of these domains were evaluated on the base of proteolysis data.
对纤维蛋白原片段DH(分子量95 kDa)的进一步蛋白水解降解进行了详细分析。从DH片段衍生出的两个新的蛋白水解片段DLA和DL已被纯化并分析。所得结果有助于通过逐步拆分其各个结构域来提出DH片段蛋白水解的总体方案。基于蛋白水解数据评估了这些结构域的边界和分子量。