Marenco-Hillembrand Lina, Alvarado-Estrada Keila, Chaichana Kaisorn L
Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, United States.
Front Oncol. 2018 Nov 28;8:558. doi: 10.3389/fonc.2018.00558. eCollection 2018.
A subset of metastatic brain tumors occurs in deep-seated locations. Accessing and resecting these lesions can be associated with significant morbidity because it involves large craniotomies, extensive white matter dissection, prolonged retraction, and risk of inadvertent tissue injury. As a result, only palliative treatment options are typically offered for these lesions including observation, needle biopsies, and/or radiation therapy. With the development of new surgical tools and techniques, minimally invasive techniques have allowed for the treatment of these lesions previously associated with significant morbidity. These minimally invasive techniques include laser interstitial thermal therapy and channel-based resections.
一部分转移性脑肿瘤发生在深部位置。切除这些病灶可能会导致严重的并发症，因为这涉及到大开颅手术、广泛的白质分离、长时间的牵拉以及意外组织损伤的风险。因此，对于这些病灶通常只提供姑息性治疗选择，包括观察、穿刺活检和/或放射治疗。随着新的手术工具和技术的发展，微创技术已能够治疗这些以前与严重并发症相关的病灶。这些微创技术包括激光间质热疗和基于通道的切除术。
