腮腺肿瘤细针穿刺细胞学检查的价值：单机构996例病例回顾
Values of fine-needle aspiration cytology of parotid gland tumors: A review of 996 cases at a single institution.
作者信息
Suzuki Manabu, Kawata Ryo, Higashino Masaaki, Nishikawa Shuji, Terada Tetsuya, Haginomori Shin-Ichi, Kurisu Yoshitaka, Hirose Yoshinobu
机构信息
Department of Otorhinolaryngology-Head and Neck Surgery, Osaka Medical College, Osaka, Japan.
Department of Pathology, Osaka Medical College, Osaka, Japan.
出版信息
Head Neck. 2019 Feb;41(2):358-365. doi: 10.1002/hed.25503. Epub 2018 Dec 9.
BACKGROUND
We evaluated the diagnostic accuracy of fine-needle aspiration cytology (FNAC) in a large series of benign and malignant parotid tumors.
METHODS
The FNAC diagnosis of 821 benign and 175 malignant parotid tumors managed at our department between 1999 and 2017 was correlated with the final histology.
RESULTS
FNAC made a correct histopathological diagnosis in 72% of the benign parotid tumors; however, FNAC provided a correct grade in only 34% of the malignant tumors. FNAC correctly identified the histology of 94% of pleomorphic adenomas subsequently confirmed by histopathological examination. The sensitivity, specificity, and diagnostic accuracy of FNAC for detecting malignancy were 82.3%, 98.7%, and 95.9%, respectively.
CONCLUSION
FNAC generally provided the correct histological diagnosis for benign tumors. However, the histological evaluation and grading of malignant tumors were poor. Although FNAC showed good sensitivity, specificity, and accuracy, its sensitivity decreased when nondiagnostic cases were included in the analysis.
背景
我们评估了细针穿刺细胞学检查（FNAC）在大量腮腺良恶性肿瘤中的诊断准确性。
方法
将1999年至2017年间在我科接受治疗的821例腮腺良性肿瘤和175例腮腺恶性肿瘤的FNAC诊断结果与最终组织学结果进行对比。
结果
FNAC对72%的腮腺良性肿瘤做出了正确的组织病理学诊断；然而，FNAC仅对34%的恶性肿瘤给出了正确的分级。FNAC正确识别了94%随后经组织病理学检查证实的多形性腺瘤的组织学类型。FNAC检测恶性肿瘤的敏感性、特异性和诊断准确性分别为82.3%、98.7%和95.9%。
结论
FNAC通常能为良性肿瘤提供正确的组织学诊断。然而，其对恶性肿瘤的组织学评估和分级效果较差。尽管FNAC显示出良好的敏感性、特异性和准确性，但在分析中纳入无法诊断的病例时，其敏感性会降低。
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