Racz Jennifer M, Block Matthew S, Baum Christian L, Jakub James W
Department of Surgery, Mayo Clinic, Rochester, Minnesota.
Department of Medical Oncology, Mayo Clinic, Rochester, Minnesota.
J Surg Oncol. 2019 Jan;119(2):187-199. doi: 10.1002/jso.25330. Epub 2018 Dec 12.
Some melanomas develop a striking avidity for lymphatic spread. In spite of multiple recurrences, patients can remain years without visceral metastasis. There is clearly a biologic reason for this lymphotrophic pattern of growth and dissemination, which we have yet to uncover. In-transit metastases have widely diverse clinical presentations and can be a stubborn disease to cure. As a result, a host of treatments exist that should be tailored to the individual patient.
一些黑色素瘤对淋巴转移表现出显著的倾向。尽管多次复发，但患者可能数年都不会发生内脏转移。这种向淋巴组织生长和扩散的模式显然有生物学原因，而我们尚未发现。皮肤转移癌有广泛多样的临床表现，且可能是一种难以治愈的疾病。因此，存在许多应根据个体患者情况量身定制的治疗方法。
