Kieny M, Mauger A, Chevallier A, Pautou M P
Unité associée au CNRS 682 Morphogenèse expérimentale, Département de Biologie, Université Joseph Fourier, Grenoble, France.
Reprod Nutr Dev (1980). 1988;28(3B):673-86. doi: 10.1051/rnd:19880501.
Experimental studies have shown that the myogenic stem cells in birds migrate from the somite into the lateral plate mesoderm, where they later differentiate into muscle cells. Muscles being made up of myocytes and connective tissue cells, the interactions between these two types of cells of different embryological origins have been considered during the development of the musculature. In particular, our purpose was to focus on the genesis of the spatial organization of the musculature; we have taken advantage in this field of research of an embryological muscular dysgenesis in which the muscles lose their patterning.
实验研究表明,鸟类的生肌干细胞从体节迁移到侧板中胚层,随后在那里分化为肌肉细胞。肌肉由肌细胞和结缔组织细胞组成,在肌肉组织发育过程中,人们已经考虑到这两种不同胚胎起源的细胞之间的相互作用。特别是,我们的目的是关注肌肉组织空间组织的起源;在这一研究领域,我们利用了一种胚胎性肌肉发育不全的情况,在这种情况下,肌肉失去了其形态。