Nordin Andrew B, Diefenbach Karen, Sales Stephen P, Christensen Jeff, Besner Gail E, Kenney Brian D
Nationwide Children's Hospital, Department of Pediatric Surgery, 700 Children's Drive, Columbus, OH, 43205; State University of New York University at Buffalo, Department of General Surgery, 100 High St, Buffalo, NY 14203.
Nationwide Children's Hospital, Department of Pediatric Surgery, 700 Children's Drive, Columbus, OH, 43205; The Ohio State University College of Medicine, 370 W 9th Ave, Columbus, OH, 43210.
J Pediatr Surg. 2019 Apr;54(4):718-722. doi: 10.1016/j.jpedsurg.2018.10.064. Epub 2018 Nov 6.
Appendicitis presents on a spectrum ranging from inflammation to gangrene to perforation. Studies suggest that gangrenous appendicitis has lower postoperative infection rates relative to perforated cases. We hypothesized that gangrenous appendicitis could be successfully treated as simple appendicitis, reducing length of stay (LOS) and antibiotic usage without increasing postoperative infections.
In February 2016, we strictly defined complex appendicitis as a hole in the appendix, extraluminal fecalith, diffuse pus or a well-formed abscess. We switched gangrenous appendicitis to a simple pathway and reviewed all patients undergoing laparoscopic appendectomy for 12 months before (Group 1) and 12 months after (Group 2) the protocol change. Data collected included demographics, appendicitis classification, LOS, presence of a postoperative infection, and 30-day readmissions.
Patients in Group 1 and Group 2 were similar, but more cases of simple appendicitis occurred in Group 2. Average LOS for gangrenous appendicitis patients decreased from 2.5 to 1.4 days (p < 0.001) and antibiotic doses decreased from 5.2 to 1.3 (p < 0.001). Only one gangrenous appendicitis patient required readmission, and one patient in each group developed a superficial infection; there were no postoperative abscesses.
Gangrenous appendicitis can be safely treated as simple appendicitis without increasing postoperative infections or readmissions.
Prognosis study.
Level II.
阑尾炎的表现范围从炎症到坏疽再到穿孔。研究表明,相对于穿孔性阑尾炎,坏疽性阑尾炎的术后感染率较低。我们推测,坏疽性阑尾炎可以像单纯性阑尾炎一样成功治疗,从而缩短住院时间(LOS)并减少抗生素使用,且不会增加术后感染。
2016年2月,我们将复杂性阑尾炎严格定义为阑尾穿孔、阑尾腔外粪石、弥漫性脓液或形成良好的脓肿。我们将坏疽性阑尾炎改为简单治疗路径,并回顾了方案改变前12个月(第1组)和改变后12个月(第2组)所有接受腹腔镜阑尾切除术的患者。收集的数据包括人口统计学资料、阑尾炎分类、住院时间、术后感染情况以及30天再入院情况。
第1组和第2组患者相似,但第2组中单纯性阑尾炎病例更多。坏疽性阑尾炎患者的平均住院时间从2.5天降至1.4天(p<0.001),抗生素剂量从5.2降至1.3(p<0.001)。只有1例坏疽性阑尾炎患者需要再次入院,每组各有1例患者发生浅表感染;无术后脓肿形成。
坏疽性阑尾炎可以安全地作为单纯性阑尾炎治疗,而不会增加术后感染或再入院率。
预后研究。
二级。