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儿童阑尾炎:手术与组织病理学诊断的相关性。

Appendicitis in children: correlation between the surgical and histological diagnosis.

机构信息

Department of Surgery and Traumatology, Heim Pál National Institute of Pediatrics, 86 Üllői Road, Budapest, 1089, Hungary.

Division of Pediatric Surgery, Department of Pediatrics, Medical School, University of Pecs, 7 Jozsef Attila Street, Pecs, 7633, Hungary.

出版信息

Pediatr Surg Int. 2024 Oct 4;40(1):262. doi: 10.1007/s00383-024-05846-2.

Abstract

PURPOSE

Study was designed in order to evaluate the discrepancies between surgical and histological diagnosis in pediatric acute appendicitis (AA) and to compare the outcomes of laparoscopic (LA) and open appendectomies (OA).

METHODS

In a retrospective observational cohort, AA patients were included under 18 years of age, operated between 2011 and 2020. Surgical diagnosis was defined by the operating surgeon. The histological findings were classified as uncomplicated and complicated AA. The LOS and complications were also statistically analyzed.

RESULTS

Altogether, 1444 patients were included. Significant strong correlation and a moderate to substantial agreement were found between the surgeon's and the histopathological findings in all appendectomy cases (weighted kappa value in OA: 0.633, LA: 0.639, total sample: 0.637). If the surgeon's diagnosis was less severe than the pathologist's, the LOS was 4 (3;7) days, whereas if the surgical diagnosis was correct, the LOS was 3 (3;5) days (p < 0.0001).

CONCLUSIONS

In contrary to the literature, our study revealed a strong correlation and moderate agreement between the intraoperative and histopathological findings regarding the severity of AA. Complicated cases are distinctly recognizable during the surgery. In case the surgeon underestimates the severity of AA, the chance of complications is higher.

LEVEL OF EVIDENCE

II.

摘要

目的

本研究旨在评估小儿急性阑尾炎(AA)手术与组织学诊断之间的差异,并比较腹腔镜(LA)和开腹阑尾切除术(OA)的结果。

方法

在回顾性观察队列中,纳入了 2011 年至 2020 年间接受手术的 18 岁以下 AA 患者。手术诊断由手术医生定义。组织学发现分为单纯性和复杂性 AA。还对 LOS 和并发症进行了统计学分析。

结果

共纳入 1444 例患者。在所有阑尾切除术中,手术医生和病理学家的发现之间存在显著的强相关性和中度至大量一致性(OA 的加权 Kappa 值:0.633,LA:0.639,总样本:0.637)。如果手术医生的诊断比病理学家的诊断轻,那么 LOS 为 4(3;7)天,而如果手术诊断正确,那么 LOS 为 3(3;5)天(p<0.0001)。

结论

与文献相反,我们的研究表明,手术与组织病理学发现之间在 AA 的严重程度方面存在很强的相关性和中度一致性。复杂病例在手术中明显可识别。如果手术医生低估了 AA 的严重程度,那么发生并发症的可能性就更高。

证据水平

II 级。

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