Miller R A, Minshew B H
Department of Medicine, University of Washington, Seattle.
Rev Infect Dis. 1988 Sep-Oct;10(5):930-8. doi: 10.1093/clinids/10.5.930.
Blastocystis hominis is a protozoan organism frequently found in the human intestinal tract. Eleven consecutive patients with symptoms of enteritis and having B. hominis as the sole enteropathogen were studied in an attempt to define the association of blastocystosis with clinical disease. B. hominis could not be implicated as the etiologic agent of enteritis in any of these patients. All eleven had alternative (and usually noninfectious) explanations for their intestinal symptoms. There was no correlation between resolution of symptoms and either antiprotozoal therapy or disappearance of B. hominis from the stools. All prior reports associating B. hominis with human disease have been reviewed and provide no convincing proof of a causal relation. B. hominis is rarely, if ever, a human pathogen, and treatment directed at the eradication of B. hominis is not indicated.
人芽囊原虫是一种常在人类肠道中发现的原生生物。对连续11例有肠炎症状且人芽囊原虫为唯一肠道病原体的患者进行了研究，以确定芽囊原虫病与临床疾病的关联。在这些患者中，没有一例可将人芽囊原虫认定为肠炎的病原体。所有11例患者的肠道症状都有其他（通常是非感染性的）解释。症状的缓解与抗寄生虫治疗或粪便中人芽囊原虫的消失均无关联。对之前所有将人芽囊原虫与人类疾病相关联的报告进行了综述，未发现有令人信服的因果关系证据。人芽囊原虫极少（如果有的话）是人类病原体，因此不建议针对根除人芽囊原虫进行治疗。
