Department of Vascular and Endovascular Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Department of Vascular and Endovascular Surgery, University Hospital Heidelberg, Heidelberg, Germany.
J Vasc Surg. 2019 May;69(5):1387-1394. doi: 10.1016/j.jvs.2018.07.073. Epub 2018 Dec 13.
The objective of this study was to evaluate the incidence, timing, and potential risk factors of late endograft migration after thoracic endovascular aortic repair (TEVAR).
A retrospective analysis was conducted of 123 patients receiving TEVAR for thoracic aortic aneurysms (TAAs), dissections, penetrating aortic ulcer, intramural hematoma, or traumatic transection between January 2005 and December 2015 with a minimum imaging-based follow-up of 6 months. Imaging analysis was performed by three independent readers. Migration was defined according to the reporting standards as a stent graft shift of >10 mm relative to a primary anatomic landmark or any displacement that led to symptoms or required therapy. A standardized measurement protocol in accordance with the reporting guidelines was used. Median follow-up was 3 years (range, 0.5-10 years).
Migration occurred in nine (7.3%) patients and took place at the proximal landing zone (n = 1), overlapping zone (n = 4), or distal landing zone (n = 5), resulting in type I or type III endoleaks in 44% (n = 4/9) of the cases. All cases of migration with endoleaks underwent reintervention; 75% (n = 3/4) of the migration associated with endoleaks could have been identified on previous imaging before an endoleak occurred. Freedom from migration was 99.1% after 1 year, 94.0% after 3 years, and 86.1% after 5 years. Aortic elongation and TAA were identified as predisposing factors for migration (P = .003 and P = .01, respectively). No influence of the proximal landing zone (zone 0-4), type of aortic arch (I-III), or type of endograft on the incidence of migration was found.
Graft migration after TEVAR occurs in a relevant proportion of patients, predominantly in patients with TAA and aortic elongation. Follow-up imaging of these patients should be specifically evaluated regarding the occurrence of migration.
本研究旨在评估胸主动脉腔内修复术(TEVAR)后晚期移植物内漏的发生率、时间和潜在风险因素。
回顾性分析了 2005 年 1 月至 2015 年 12 月期间接受 TEVAR 治疗的 123 例胸主动脉瘤(TAA)、夹层、穿透性主动脉溃疡、壁内血肿或创伤性横断患者的资料,这些患者均接受了至少 6 个月的影像学随访。由 3 名独立的读者进行影像学分析。根据报告标准,将移植物移位定义为相对于主要解剖标志的支架移植物移位>10mm,或任何导致症状或需要治疗的移位。使用符合报告指南的标准化测量协议。中位随访时间为 3 年(0.5-10 年)。
9 例(7.3%)患者发生移植物内漏,近端着陆区(n=1)、重叠区(n=4)或远端着陆区(n=5),44%(n=4/9)的病例发生了Ⅰ型或Ⅲ型内漏。所有发生内漏的移植物内漏均进行了再干预;75%(n=3/4)的内漏相关移植物在发生内漏之前的影像学检查中可以识别。1 年后移植物内漏的无移植物生存率为 99.1%,3 年后为 94.0%,5 年后为 86.1%。主动脉伸长和 TAA 被认为是移植物内漏的易患因素(P=0.003 和 P=0.01)。近端着陆区(zone 0-4)、主动脉弓类型(I-III)或移植物类型对移植物内漏发生率无影响。
TEVAR 后移植物内漏在相当一部分患者中发生,主要发生在 TAA 和主动脉伸长的患者中。应对这些患者的随访影像学进行专门评估,以确定是否发生移植物内漏。