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胸主动脉腔内修复术后移植物迁移。

Endograft migration after thoracic endovascular aortic repair.

机构信息

Department of Vascular and Endovascular Surgery, University Hospital Heidelberg, Heidelberg, Germany.

Department of Vascular and Endovascular Surgery, University Hospital Heidelberg, Heidelberg, Germany.

出版信息

J Vasc Surg. 2019 May;69(5):1387-1394. doi: 10.1016/j.jvs.2018.07.073. Epub 2018 Dec 13.

Abstract

OBJECTIVE

The objective of this study was to evaluate the incidence, timing, and potential risk factors of late endograft migration after thoracic endovascular aortic repair (TEVAR).

METHODS

A retrospective analysis was conducted of 123 patients receiving TEVAR for thoracic aortic aneurysms (TAAs), dissections, penetrating aortic ulcer, intramural hematoma, or traumatic transection between January 2005 and December 2015 with a minimum imaging-based follow-up of 6 months. Imaging analysis was performed by three independent readers. Migration was defined according to the reporting standards as a stent graft shift of >10 mm relative to a primary anatomic landmark or any displacement that led to symptoms or required therapy. A standardized measurement protocol in accordance with the reporting guidelines was used. Median follow-up was 3 years (range, 0.5-10 years).

RESULTS

Migration occurred in nine (7.3%) patients and took place at the proximal landing zone (n = 1), overlapping zone (n = 4), or distal landing zone (n = 5), resulting in type I or type III endoleaks in 44% (n = 4/9) of the cases. All cases of migration with endoleaks underwent reintervention; 75% (n = 3/4) of the migration associated with endoleaks could have been identified on previous imaging before an endoleak occurred. Freedom from migration was 99.1% after 1 year, 94.0% after 3 years, and 86.1% after 5 years. Aortic elongation and TAA were identified as predisposing factors for migration (P = .003 and P = .01, respectively). No influence of the proximal landing zone (zone 0-4), type of aortic arch (I-III), or type of endograft on the incidence of migration was found.

CONCLUSIONS

Graft migration after TEVAR occurs in a relevant proportion of patients, predominantly in patients with TAA and aortic elongation. Follow-up imaging of these patients should be specifically evaluated regarding the occurrence of migration.

摘要

目的

本研究旨在评估胸主动脉腔内修复术(TEVAR)后晚期移植物内漏的发生率、时间和潜在风险因素。

方法

回顾性分析了 2005 年 1 月至 2015 年 12 月期间接受 TEVAR 治疗的 123 例胸主动脉瘤(TAA)、夹层、穿透性主动脉溃疡、壁内血肿或创伤性横断患者的资料,这些患者均接受了至少 6 个月的影像学随访。由 3 名独立的读者进行影像学分析。根据报告标准,将移植物移位定义为相对于主要解剖标志的支架移植物移位>10mm,或任何导致症状或需要治疗的移位。使用符合报告指南的标准化测量协议。中位随访时间为 3 年(0.5-10 年)。

结果

9 例(7.3%)患者发生移植物内漏,近端着陆区(n=1)、重叠区(n=4)或远端着陆区(n=5),44%(n=4/9)的病例发生了Ⅰ型或Ⅲ型内漏。所有发生内漏的移植物内漏均进行了再干预;75%(n=3/4)的内漏相关移植物在发生内漏之前的影像学检查中可以识别。1 年后移植物内漏的无移植物生存率为 99.1%,3 年后为 94.0%,5 年后为 86.1%。主动脉伸长和 TAA 被认为是移植物内漏的易患因素(P=0.003 和 P=0.01)。近端着陆区(zone 0-4)、主动脉弓类型(I-III)或移植物类型对移植物内漏发生率无影响。

结论

TEVAR 后移植物内漏在相当一部分患者中发生,主要发生在 TAA 和主动脉伸长的患者中。应对这些患者的随访影像学进行专门评估,以确定是否发生移植物内漏。

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