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基于起源部位的鼻窦内翻性乳头状瘤分期系统在鼻内镜鼻窦手术中的应用

Origin site-based staging system of sinonasal inverted papilloma for application to endoscopic sinus surgery.

作者信息

Meng Yifan, Fang Gaoli, Wang Xiangdong, Song Xiaohong, Wang Kuiji, Lou Hongfei, She Wenyu, Qin Long, Lv Mei, Zhang Tao, Yuan Tiejun, Tao Yanli, Meng Xun, Zhang Luo, Wang Chengshuo

机构信息

Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China.

Department of Otolaryngology, Head and Neck Surgery, Beijing Ditan Hospital, Capital Medical University, Beijing, China.

出版信息

Head Neck. 2019 Feb;41(2):440-447. doi: 10.1002/hed.25435. Epub 2018 Dec 15.

Abstract

BACKGROUND

We aimed to assess the recurrence risk of sinonasal inverted papillomas (SNIPs), based on a staging system developed according to the originating site of SNIP.

METHODS

A total of 200 patients with SNIP were enrolled, and a staging system was developed based on the originating sites and corresponding recurrence rates of tumor in the patients. In the verification phase, 675 patients with SNIPs were enrolled as above, and the originating sites of the SNIPs were confirmed by an endoscopic sinus surgery. Cluster analysis was performed to determine the stage for each SNIP.

RESULTS

Overall, 608 patients completed the study. SNIP recurrence rates for stages 1-4 were 0 (n = 43), 4.0% (n = 420), 13.4% (n = 134), 36.4% (n = 11), respectively (total = 6.4%).

CONCLUSIONS

The origin site-based classification of SNIP may aid surgeons in selecting appropriate endoscopic surgical approaches to minimize the risk of recurrence.

摘要

背景

我们旨在基于根据鼻窦内翻性乳头状瘤(SNIPs)起源部位制定的分期系统,评估其复发风险。

方法

共纳入200例SNIP患者,并根据患者肿瘤的起源部位及相应复发率制定分期系统。在验证阶段,按上述方法纳入675例SNIP患者,通过鼻内镜鼻窦手术确认SNIP的起源部位。进行聚类分析以确定每个SNIP的分期。

结果

总体而言,608例患者完成了研究。1 - 4期SNIP的复发率分别为0(n = 43)、4.0%(n = 420)、13.4%(n = 134)、36.4%(n = 11)(总计 = 6.4%)。

结论

基于起源部位的SNIP分类可能有助于外科医生选择合适的内镜手术方法,以降低复发风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f210/6590184/2cf4a99fae61/HED-41-440-g001.jpg

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