Department of Plastic and Reconstructive Surgery, Hand Surgery and Burn Care Center, University Hospital of Witten/Herdecke, Cologne, Germany.
Plastic Surgery and Dermatology Center, International Medical Center, Jeddah, Saudi Arabia.
J Tissue Eng Regen Med. 2019 Feb;13(2):253-260. doi: 10.1002/term.2788. Epub 2019 Jan 4.
During the last three decades, tissue engineering and reconstructive surgery have become standard therapeutic options in the world of medicine. Several biomaterials, either alone or in combination with cultured cellular products, have been introduced to compensate for the scarcity of autologous donor tissue or to improve healing in a variety of surgical specialties, for example, abdominal/visceral surgery, plastic surgery, and cardiovascular surgery. Many of these biomaterials are of porcine origin. It is well known that Islam has prohibited the consumption of porcine or any of its products. With Muslims accounting for 23% (1.6 billion) of the global population, a thorough review of the implications of porcine-derived tissue-engineered products in surgery seems necessary. In life-threatening conditions as well as severe diseases, the use of porcine-derived products is permissible if similar non-porcine-derived materials are not available. In this case, the use of porcine-derived products represents a necessity and is allowed. Therefore, this distinction between sole need and necessity has great importance not only for the medical community but also for researchers in biotechnology and industry who may consider alternatives to porcine-derived materials.
在过去的三十年中，组织工程和重建外科已经成为医学领域的标准治疗选择。已经引入了几种生物材料，无论是单独使用还是与培养的细胞产品结合使用，都是为了弥补自体供体组织的不足，或者改善各种外科专业的愈合，例如腹部/内脏外科、整形外科学和心血管外科学。这些生物材料中有许多来自猪。众所周知，伊斯兰教禁止食用猪肉或其任何产品。由于穆斯林占全球人口的 23%（16 亿），因此似乎有必要彻底审查手术中源自猪的组织工程产品的影响。在危及生命的情况以及严重疾病中，如果没有类似的非猪源性材料可用，使用源自猪的产品是允许的。在这种情况下，使用源自猪的产品是必要的，因此是允许的。因此，这种仅需和必要之间的区别不仅对医学界，而且对生物技术和工业领域的研究人员也非常重要，他们可能会考虑替代源自猪的材料。
