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特发性室性心律失常的导管消融术

Catheter Ablation of Idiopathic Ventricular Arrhythmias.

作者信息

Pathak Rajeev K, Ariyarathna Nilshan, Garcia Fermin C, Sanders Prashanthan, Marchlinski Francis E

机构信息

Canberra Hospital, Australian National University, Canberra, ACT, Australia.

Canberra Hospital, Australian National University, Canberra, ACT, Australia.

出版信息

Heart Lung Circ. 2019 Jan;28(1):102-109. doi: 10.1016/j.hlc.2018.10.012. Epub 2018 Oct 17.

Abstract

Ventricular arrhythmias (VA) are observed in the setting of structural heart disease. However, in a proportion of patients presenting with VT, the routine diagnostic modalities fail to demonstrate overt myocardial abnormality. These arrhythmias have been called idiopathic VAs. They consist of various subtypes that have been defined by their anatomic location of origin within the heart and/or their underlying mechanism. While the majority of patients are asymptomatic, some experience debilitating symptoms and may develop reversible ventricular dysfunction. Catheter ablation has been traditionally reserved for patients with incapacitating symptoms or progressive ventricular dysfunction. However, as many patients are young, and catheter ablation can be curative in >90% of cases with a low risk (<1%) of serious complications, it is increasingly being offered as a first-line treatment in symptomatic patients. The approach to arrhythmia mapping is guided by the 12-lead electrocardiograph (ECG) morphology of the ventricular tachycardia (VT). Use of three dimensional (3D) electroanatomic mapping systems and intra-cardiac echocardiography are helpful in localising sites for successful ablation.

摘要

室性心律失常(VA)见于结构性心脏病患者。然而,在一部分出现室性心动过速(VT)的患者中,常规诊断方法未能显示明显的心肌异常。这些心律失常被称为特发性VA。它们由各种亚型组成,这些亚型根据其在心脏内的起源解剖位置和/或其潜在机制来定义。虽然大多数患者无症状,但有些患者会出现使人衰弱的症状,并可能发展为可逆性心室功能障碍。传统上,导管消融术仅适用于有失能症状或进行性心室功能障碍的患者。然而,由于许多患者较为年轻,且导管消融术在超过90%的病例中可治愈,严重并发症风险低(<1%),因此越来越多地被作为有症状患者的一线治疗方法。心律失常标测方法以室性心动过速(VT)的12导联心电图(ECG)形态为指导。使用三维(3D)电解剖标测系统和心内超声心动图有助于定位成功消融的部位。

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