Watschinger B, Sonnleitner A, Schwarz M, Mühlbacher F, Kovarik J
II. Medizinische Universitätsklinik, Wien.
Wien Klin Wochenschr. 1988 Sep 9;100(17):581-4.
A retrospective analysis was undertaken of the renal transplantation results in diabetic nephropathy over the past 10 years. Out of 428 kidney transplants in 348 patients, 22 transplants were performed in 20 diabetic patients during the observation period. Patient survival for diabetics after 1, 2, and 3 years in contrast to non-diabetic controls was significantly different (70%, 50.9%, 50.9%, respectively versus 93.9%, 89.5%, 83.3% in the non-diabetic control group) (p less than 0.001). Transplant survival was 55%, 42%, 34.4%, versus 74.7%, 67.4%, 57.6% after 1, 2, and 3 years, respectively (p less than 0.08). During the posttransplant period the incidence of cardiovascular and infectious complications, as well as the rate of amputation was much higher than in the pretransplant phase. Main causes of death were cardiovascular or infectious complications. Improvement of the still poor results in diabetic transplant recipients is certainly a challenge for the future.
对过去10年糖尿病肾病患者肾移植结果进行了回顾性分析。在348例患者的428例肾移植中，观察期内20例糖尿病患者进行了22例移植。与非糖尿病对照组相比，糖尿病患者1年、2年和3年后的患者生存率有显著差异（分别为70%、50.9%、50.9%，而非糖尿病对照组为93.9%、89.5%、83.3%）（p<0.001）。移植肾生存率1年、2年和3年后分别为55%、42%、34.4%，而非糖尿病对照组分别为74.7%、67.4%、57.6%（p<0.08）。移植后心血管和感染并发症的发生率以及截肢率远高于移植前阶段。主要死亡原因是心血管或感染并发症。改善糖尿病移植受者仍然较差的结果无疑是未来的一项挑战。
