Sorkin Nir, Kreimei Mohammad, Einan-Lifshitz Adi, Mednick Zale, Belkin Avner, Chan Clara C, Slomovic Allan R, Rootman David S
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.
Ophthalmology Department, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Cornea. 2019 Mar;38(3):285-289. doi: 10.1097/ICO.0000000000001830.
To report the outcome of wavefront-guided photorefractive keratectomy (WG-PRK) in the treatment of high astigmatism following keratoplasty.
A retrospective, interventional analysis including patients with high astigmatism following either penetrating keratoplasty or deep anterior lamellar keratoplasty, who underwent WG-PRK.
Thirteen eyes (7 right eyes) of 12 patients (10 male) aged 35.1 ± 5.9 years were included. Preoperative astigmatism ranged between 3.00 and 5.00 D. Average follow-up time was 14.0 ± 6.2 months. Uncorrected distance visual acuity (UDVA) improved from 0.97 ± 0.58 logarithm of the minimum angle of resolution (logMAR) (Snellen equivalent ∼20/187) preoperatively to 0.13 ± 0.15 logMAR (Snellen equivalent ∼20/27) at 6 months and 0.14 ± 0.16 logMAR (Snellen equivalent ∼20/28) at the final follow-up (P = 0.001 and P = 0.002, respectively). UDVA ≥20/40 increased from 1 eye (7.7%) preoperatively to 13 eyes (100%) at 6 months and 12 eyes (92.3%) at the final follow-up (P < 0.001 for both). UDVA ≥20/25 increased from 1 eye (7.7%) preoperatively to 6 eyes (46.2%) at 6 months and at the final follow-up (P = 0.027 for both). Mean astigmatism improved from -3.98 ± 0.75 D to -1.27 ± 0.82 D and -1.40 ± 1.04 at 6 months and at the last follow-up, respectively (P = 0.001 for both). Preoperative astigmatism was ≥3.00 D in all eyes and was reduced to ≤2.50 D in all eyes at 6 months postoperatively, with 7 eyes (63.6%) having ≤1.00 D of astigmatism at both 6 months and the final follow-up.
WG-PRK was safe and effective in the treatment of high and regular postkeratoplasty astigmatism.
报告波前引导准分子原位角膜磨镶术（WG-PRK）治疗角膜移植术后高度散光的效果。
一项回顾性干预分析，纳入穿透性角膜移植术或深板层角膜移植术后发生高度散光并接受WG-PRK治疗的患者。
纳入12例患者（10例男性）的13只眼（7只右眼），年龄35.1±5.9岁。术前散光度数在3.00至5.00 D之间。平均随访时间为14.0±6.2个月。未矫正远视力（UDVA）从术前的0.97±0.58最小分辨角对数（logMAR）（Snellen视力表等效值约为20/187）提高到6个月时的0.13±0.15 logMAR（Snellen视力表等效值约为20/27）以及末次随访时的0.14±0.16 logMAR（Snellen视力表等效值约为20/28）（分别为P = 0.001和P = 0.002）。UDVA≥20/40的比例从术前的1只眼（7.7%）增加到6个月时的13只眼（100%）以及末次随访时的12只眼（92.3%）（两者P均<0.001）。UDVA≥20/25的比例从术前的1只眼（7.7%）增加到6个月时和末次随访时的6只眼（46.2%）（两者P = 0.027）。平均散光度数分别从-3.98±0.75 D改善到6个月时的-1.27±0.82 D以及末次随访时的-1.40±1.04 D（两者P = 0.001）。所有眼术前散光度数均≥3.00 D，术后6个月时所有眼散光度数均降至≤2.50 D，6个月和末次随访时均有7只眼（63.6%）散光度数≤1.00 D。
WG-PRK治疗角膜移植术后高度规则散光安全有效。
