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急性 A 型主动脉夹层管理的新模式:全主动脉修复。

A new paradigm in the management of acute type A aortic dissection: Total aortic repair.

机构信息

Department of Cardiac Surgery, Austin Hospital, Heidelberg, Australia.

Department of Cardiac Surgery, Austin Hospital, Heidelberg, Australia.

出版信息

J Thorac Cardiovasc Surg. 2019 Jan;157(1):3-11. doi: 10.1016/j.jtcvs.2018.08.118. Epub 2018 Oct 13.

Abstract

The currently accepted guidelines of open surgical repair for acute type A aortic dissection include the resection of the primary entry tear, replacement of the ascending aorta and "hemi-arch" with an open distal anastomosis, and aortic valve resuspension and some form of obliteration of the aortic root false lumen. The principal aim is protection against aortic rupture, aortic regurgitation, and coronary ischemia and restoration of antegrade preferential true lumen perfusion. Proponents argue that this operation is tailored to be in the armamentarium of most cardiac surgeons and deliver the lowest early operative risk while leaving the infrequent long-term sequelae to be dealt with electively by experienced aortic centers. Although this may sound to be a compelling argument, the actual outcomes suggest that it falls significantly short of achieving its noble goals on both acute and chronic counts. This led us to develop a seemingly more radical paradigm, which aims to achieve total aortic healing in the acute phase. We describe a total aortic repair technique for acute type A aortic dissection consisting of "branch first" total arch repair, followed by thoracoabdominal stenting and balloon rupture of the septum. The total aortic repair technique ensures that the aortic valve, ascending aorta, and arch are surgically securely repaired, and provides complete decompression of the false lumen as well as internal support in the remainder of the aorta. This has provided excellent early results and will hopefully minimize future complications and interventions.

摘要

目前,接受的急性 A 型主动脉夹层开放手术修复指南包括切除原发性入口撕裂,用开放式远端吻合术替换升主动脉和“半弓”,以及主动脉瓣悬吊和某种形式的主动脉根部假腔闭塞。主要目的是防止主动脉破裂、主动脉反流和冠状动脉缺血,并恢复顺行优势真腔灌注。支持者认为,这种手术是大多数心脏外科医生的必备手术,可以降低早期手术风险,而将罕见的长期后果留给有经验的主动脉中心选择性处理。尽管这听起来是一个有说服力的论点,但实际结果表明,它在急性和慢性方面都远远没有达到其崇高目标。这促使我们开发了一种看似更激进的范例,旨在在急性期实现完全的主动脉愈合。我们描述了一种用于急性 A 型主动脉夹层的全主动脉修复技术,包括“分支第一”全弓修复,随后进行胸腹支架和分隔破裂球囊扩张。全主动脉修复技术确保了主动脉瓣、升主动脉和弓部得到了安全的手术修复,并提供了假腔的完全减压以及主动脉其余部分的内部支撑。这提供了极好的早期结果,并有望最大限度地减少未来的并发症和干预。

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