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妇科病理学中冰冻切片的陷阱:一例模仿恶性肿瘤的卵巢浆液性表面乳头状腺纤维瘤

Pitfalls of Frozen Section in Gynecological Pathology: A Case of Ovarian Serous Surface Papillary Adenofibroma Imitating Malignancy.

作者信息

Jones Anja M K, Yue Wei Ying, Marcus Jenna, Heller Debra S

机构信息

1 Rutgers-New Jersey Medical School, Newark, NJ, USA.

出版信息

Int J Surg Pathol. 2019 May;27(3):268-270. doi: 10.1177/1066896918818894. Epub 2018 Dec 18.

DOI:10.1177/1066896918818894
PMID:30563377
Abstract

Serous cystadenofibromas are uncommon benign ovarian lesions, consisting of both fibrous and epithelial components, that are usually cystic but may contain solid or papillary architecture that can be confused with a malignancy on imaging. Papillary architecture seen on frozen section may also falsely steer the pathologist in the direction of a diagnosis of a borderline serous tumor. Overcalling the lesion may lead to more aggressive surgery than necessary, so extensive tissue sampling and consideration of this entity is important in possibly avoiding this mistake.

摘要

浆液性囊腺纤维瘤是一种罕见的卵巢良性病变,由纤维和上皮成分组成,通常为囊性,但可能包含实性或乳头状结构,在影像学上可能与恶性肿瘤混淆。冰冻切片上可见的乳头状结构也可能误导病理学家做出交界性浆液性肿瘤的诊断。对病变的过度诊断可能导致不必要的更激进手术,因此广泛的组织取样并考虑到这种病变对于可能避免这种错误很重要。

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引用本文的文献

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J Obstet Gynaecol Res. 2021 Dec;47(12):4496-4501. doi: 10.1111/jog.15018. Epub 2021 Sep 6.