Ogryz'ko E P, Nikiforov V G, Borodin A M, Danilkovich A V, Monastyrskaia G S
Bioorg Khim. 1988 Jul;14(7):963-4.
Ts-phenotype of the E. coli rho-factor mutant rho 15 is suppressed by two rifampicin-resistance mutations, rhoB1019 resulting in a single amino acid substitution Val146----Phe and rhoB268 resulting in a single substitution Gln513----Leu in beta-subunit of the E. coli RNA polymerase. Rifampicin-resistance mutations rhoB255 (Asp516----Val), rhoB1016 (Asp516----Asn), rhoB1001 (His526----Tyr), rhoB1004 (Ser531----Phe), rhoB1005 (Pro564----Leu), and streptolydigin-resistance' mutation rhoB1018 (double substitution Gly544----Asp and Phe545----Ser) do not suppress the rho15 mutation.
大肠杆菌rho因子突变体rho 15的Ts表型被两个利福平抗性突变所抑制，rhoB1019导致单个氨基酸取代Val146→Phe，rhoB268导致大肠杆菌RNA聚合酶β亚基中单个取代Gln513→Leu。利福平抗性突变rhoB255（Asp516→Val）、rhoB1016（Asp516→Asn）、rhoB1001（His526→Tyr）、rhoB1004（Ser531→Phe）、rhoB1005（Pro564→Leu）以及链霉溶菌素抗性突变rhoB1018（双重取代Gly544→Asp和Phe545→Ser）均不能抑制rho15突变。
