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From the neo-Kraepelinian framework to the new mechanical philosophy of psychiatry: regaining common sense.

作者信息

Joober Ridha, Tabbane Karim

机构信息

From the Research Centre, Douglas University Institute, Montreal, Que., Canada; and the Department of Psychiatry, McGill University, Montreal, Que., Canada.

出版信息

J Psychiatry Neurosci. 2019 Jan 1;44(1):3-7. doi: 10.1503/jpn.180240.

DOI:10.1503/jpn.180240
PMID:30565447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6306285/
Abstract
摘要

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JAMA Psychiatry. 2018 Nov 1;75(11):1146-1155. doi: 10.1001/jamapsychiatry.2018.2467.
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Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.全基因组关联荟萃分析在 269867 个人中确定了与智力有关的新的遗传和功能联系。
Nat Genet. 2018 Jul;50(7):912-919. doi: 10.1038/s41588-018-0152-6. Epub 2018 Jun 25.
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Analysis of shared heritability in common disorders of the brain.脑常见疾病的遗传共享分析。
Science. 2018 Jun 22;360(6395). doi: 10.1126/science.aap8757.
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Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.全基因组关联分析确定了 30 个精神分裂症的新易感性位点。
Nat Genet. 2017 Nov;49(11):1576-1583. doi: 10.1038/ng.3973. Epub 2017 Oct 9.
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Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.边缘型人格障碍的全基因组关联研究揭示了其与双相情感障碍、重度抑郁症和精神分裂症的遗传重叠。
Transl Psychiatry. 2017 Jun 20;7(6):e1155. doi: 10.1038/tp.2017.115.
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An Expanded View of Complex Traits: From Polygenic to Omnigenic.复杂性状的扩展观点:从多基因到泛基因
Cell. 2017 Jun 15;169(7):1177-1186. doi: 10.1016/j.cell.2017.05.038.
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.对超过16000名自闭症谱系障碍患者进行全基因组关联研究的荟萃分析,发现了一个位于10q24.32的新基因座,且与精神分裂症存在显著重叠。
Mol Autism. 2017 May 22;8:21. doi: 10.1186/s13229-017-0137-9. eCollection 2017.
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Am J Psychiatry. 2017 Feb 1;174(2):102-109. doi: 10.1176/appi.ajp.2016.16030375. Epub 2016 Aug 13.
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The transformation of American psychiatric nosology at the dawn of the twentieth century.二十世纪初美国精神病学分类法的转变。
Mol Psychiatry. 2016 Feb;21(2):152-8. doi: 10.1038/mp.2015.188. Epub 2015 Dec 22.
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Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.使用快速方差成分分析对比精神分裂症和其他复杂疾病的遗传结构。
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