Zwahlen A, Regamey C
Schweiz Med Wochenschr. 1978 Apr 1;108(13):477-82.
Two adults were admitted to the University Hospital of Geneva with acute Haemophilus influenzae type b epiglottitis. The disease was characterized by rapid progression of sore throat, upper dysphagia, fever and dyspnea. Acute upper airway obstruction required emergency tracheotomy in both cases. The patients recovered under ampicillin therapy. All the 100 cases from the literature for which clinical data were available have been analyzed:--Epiglottitis in adult is not exceptional.--Haemophilus influenzae type b is the most common infective organism documented, and was found in all positive blood cultures but one.--The typical presentation is severe sore throat, with upper dysphagia, fever and dyspnea.--Clinical course is rapid and serious, and acute respiratory distress develops in 57% of cases; overall mortality is 27%.--Emergency routine tracheotomy appears to be the most reliable treatment.
两名成人因急性b型流感嗜血杆菌会厌炎入住日内瓦大学医院。该病的特征为咽痛迅速加重、上吞咽困难、发热和呼吸困难。两例均因急性上气道梗阻而行紧急气管切开术。患者在氨苄西林治疗下康复。对文献中可获得临床资料的所有100例病例进行了分析：——成人会厌炎并不罕见。——b型流感嗜血杆菌是记录中最常见的感染病原体，除1例血培养阳性外，其余所有血培养阳性病例均发现该菌。——典型表现为严重咽痛、上吞咽困难、发热和呼吸困难。——临床病程迅速且严重，57%的病例会出现急性呼吸窘迫；总体死亡率为27%。——紧急常规气管切开术似乎是最可靠的治疗方法。
