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[用星状诺卡菌(生物变种A3)成功治疗肺部感染]

[Successful antibiotic treatment of a pulmonary infection with Nocardia asteroides (biovariety A3)].

作者信息

Ruppert S, Reinold H M, Jipp P, Schröter G, Egner E, Schaal K P

机构信息

Abteilung Allgemeine Innere Medizin, Katharinenhospital der Stadt Stuttgart.

出版信息

Dtsch Med Wochenschr. 1988 Nov 18;113(46):1801-5. doi: 10.1055/s-2008-1067891.

Abstract

An open lung biopsy in a 67-year-old man revealed nocardiosis as the cause of a treatment-resistant pulmonary infection. His resistance had been weakened by a non-Hodgkin lymphoma, polychemotherapy and long-term steroid medication. The nocardiosis was cured by a 26-day high-dosage regimen of imipenem and amikacin in combination. A six-month period of co-trimoxazole followed to ensure treatment success. Nocardia asteroides (biovariety A3) was found to be the causative organism, the second time that this has been described as cause of a human infection.

摘要

一名67岁男性的开胸肺活检显示,诺卡菌病是导致其难治性肺部感染的原因。他的抵抗力因非霍奇金淋巴瘤、多药化疗和长期使用类固醇药物而减弱。通过亚胺培南和丁胺卡那霉素联合使用26天的高剂量方案治愈了诺卡菌病。随后服用复方新诺明六个月以确保治疗成功。发现星形诺卡菌(生物变种A3)是病原体,这是该菌第二次被描述为人类感染的病因。

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