Covelli V, Jirillo E
Chair of Clinical Neuroanatomy, Faculty of Medicine and Surgery, University of Bari, Italy.
Funct Neurol. 1988 Jul-Sep;3(3):253-61.
Neuropeptides (NP) from the central nervous system and the peripheral nervous system play a modulating role in the immune system. In principle, all immunological functions are influenced by NP either in terms of nonspecific immunity or cellular immunity. In the present review, some aspects of this interaction are summarized, namely the existence of receptors for NP on immune cells and the production of NP by leukocytes. Finally, the pathogenetic role of NP in diseases and the future perspectives of neuroimmunology are outlined.
来自中枢神经系统和外周神经系统的神经肽在免疫系统中发挥调节作用。原则上，所有免疫功能在非特异性免疫或细胞免疫方面都会受到神经肽的影响。在本综述中，总结了这种相互作用的一些方面，即免疫细胞上神经肽受体的存在以及白细胞产生神经肽的情况。最后，概述了神经肽在疾病中的致病作用以及神经免疫学的未来前景。
