表现为“靶征”的转移性恶性淋巴瘤酷似脑弓形虫病。
Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the "Target Sign".
作者信息
Ueno Hiroki, Norose Kazumi, Kamimura Teppei, Mihara Keichiro, Yamasaki Fumiyuki, Hikosaka Kenji, J Amatya Vishwa, Takeshima Yukio, Kurisu Kaoru, Maruyama Hirofumi
机构信息
Department of Clinical Neuroscience and Therapeutics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan.
Department of Infection and Host Defense, Graduate School of Medicine, Chiba University, Japan.
出版信息
Intern Med. 2019 Apr 15;58(8):1157-1162. doi: 10.2169/internalmedicine.1156-18. Epub 2018 Dec 18.
We herein report the case of a 60-year-old man with a "target sign" in the left frontal lobe on magnetic resonance imaging (MRI), which is thought to be a specific sign of cerebral toxoplasmosis. F-fluorodeoxyglucose-positron emission tomography showed no increased uptake, and Tl-single photon emission computed tomography showed the focal uptake in the left frontal lesion. On a brain biopsy, the patient was given a definitive diagnosis of brain metastasis from diffuse large B-cell lymphoma, and cerebral toxoplasmosis was excluded. In the present case, multilayer intensities on MRI may reflect the fast-growing nature of this tumor.
我们在此报告一例60岁男性，其磁共振成像（MRI）显示左额叶有“靶征”，该征象被认为是脑弓形虫病的特异性征象。氟脱氧葡萄糖正电子发射断层扫描显示摄取未见增加，而铊单光子发射计算机断层扫描显示左额叶病变处有局灶性摄取。经脑活检，该患者被明确诊断为弥漫性大B细胞淋巴瘤脑转移，排除了脑弓形虫病。在本病例中，MRI上的多层强度可能反映了该肿瘤生长迅速的特性。
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