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白内障手术中灌注动态压力辅助水分离对眼压及后房-前玻璃体膜屏障的影响

Influence of irrigation dynamic pressure-assisted hydrodissection on intraocular pressure and the posterior chamber-anterior hyaloid membrane barrier during cataract surgery.

作者信息

Kato Noriko, Masuda Yoichiro, Oki Kotaro, Iwaki Hisaharu, Tsuneoka Hiroshi

机构信息

Department of Ophthalmology, School of Medicine, The Jikei University, 3-25-8 Nishishinbashi, Minato-ku, Tokyo, 105-8461, Japan.

Oki Eye Surgery Center, Tokyo, Japan.

出版信息

Jpn J Ophthalmol. 2019 Mar;63(2):221-228. doi: 10.1007/s10384-018-00646-3. Epub 2018 Dec 19.

DOI:10.1007/s10384-018-00646-3
PMID:30569378
Abstract

PURPOSE

To evaluate the effects of irrigation dynamic pressure-assisted hydrodissection (irrigation-hydro: iH) on intraocular pressure (IOP) and the posterior chamber-anterior hyaloid membrane (PC-AHM) barrier in porcine eyes.

STUDY DESIGN

Experimental.

METHODS

In Experiment 1, IOP was recorded while irrigating the anterior chamber (AC), during iH, and during phacoemulsification and aspiration in 20 porcine eyes using bottle heights of 50, 70, and 90 cm. Under the same conditions, IOP was recorded during conventional manual cortical cleaving hydrodissection (manual hydro: mH) in 20 porcine eyes. In Experiment 2, after iH, ACs were perfused for 5 seconds with balanced salt solution containing 1.0-μm fluorescein beads in 20 porcine eyes using bottle heights of 70, 118, and 169 cm. PC-AHM barrier staining grade was evaluated by the Miyake-Apple view.

RESULTS

iH proved successful in all cases. In Experiment 1, IOP during iH was relatively stable and peak IOP was below the baseline bottle height-dependent pressure. No eyes showed a peak IOP > 75 mmHg during iH, but 8 eyes showed a peak IOP > 75 mmHg during mH. In Experiment 2, neither AHT nor ruptured capsules were observed at any bottle height.

CONCLUSION

Unlike mH, IOP during iH was relatively stable without any high peak IOP. Thus, iH offers a simple technique for reducing peak IOP and avoiding disturbance of the PC-AHM barrier.

摘要

目的

评估灌注动态压力辅助水分离术(灌注-水分离:iH)对猪眼眼压(IOP)及后房-前玻璃体膜(PC-AHM)屏障的影响。

研究设计

实验性研究。

方法

在实验1中,使用50、70和90厘米的瓶高,对20只猪眼在前房灌注、iH期间以及超声乳化吸除过程中记录眼压。在相同条件下,对20只猪眼进行传统手动皮质劈开式水分离术(手动水分离:mH)时记录眼压。在实验2中,iH后,使用70、118和169厘米的瓶高,对20只猪眼的前房用含1.0微米荧光素珠的平衡盐溶液灌注5秒。通过三浦-苹果视图评估PC-AHM屏障染色分级。

结果

所有病例中iH均成功。在实验1中,iH期间眼压相对稳定,眼压峰值低于基线瓶高相关压力。iH期间没有眼睛的眼压峰值>75 mmHg,但mH期间有8只眼睛的眼压峰值>75 mmHg。在实验2中,在任何瓶高下均未观察到高眼压或囊膜破裂。

结论

与mH不同,iH期间眼压相对稳定,无任何高眼压峰值。因此,iH提供了一种降低眼压峰值并避免干扰PC-AHM屏障的简单技术。

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本文引用的文献

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Irrigation dynamic pressure-assisted hydrodissection during cataract surgery.白内障手术中冲洗动态压力辅助水分离术
Clin Ophthalmol. 2017 Feb 14;11:323-328. doi: 10.2147/OPTH.S124528. eCollection 2017.
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Hydrodissection-free phacoemulsification surgery: mechanical cortical cleaving dissection.免水分离白内障超声乳化手术:机械性皮质劈开分离术
J Cataract Refract Surg. 2014 Aug;40(8):1327-31. doi: 10.1016/j.jcrs.2014.06.023.
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Influence of elevated intraocular pressure on the posterior chamber-anterior hyaloid membrane barrier during cataract operations.白内障手术期间眼压升高对后房-前玻璃体膜屏障的影响。
Arch Ophthalmol. 2011 Jun;129(6):751-7. doi: 10.1001/archophthalmol.2011.115.
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Fate of anterior capsule tears during cataract surgery.白内障手术中前囊膜撕裂的转归
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Intraocular pressure during phacoemulsification.白内障超声乳化吸除术中的眼压
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New classification of capsular block syndrome.晶状体囊膜阻滞综合征的新分类
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