使用马的真空气流系统对一种原型动态喉成形术系统进行体外评估。

Evaluation of a prototype dynamic laryngoplasty system in vitro with an equine vacuum airflow system.

作者信息

Ahern Benjamin J, Lukas Emily, Lam Kimberly, Wilke Emma, Bertin Francois-Rene, Van Eps Andrew, Franklin Samantha

机构信息

Equine Specialist Hospital, School of Veterinary Science, University of Queensland, UQ Gatton Campus, Gatton, Queensland, Australia.

Equine Health and Performance Centre, University of Adelaide, Roseworthy, South Australia, Australia.

出版信息

Vet Surg. 2019 Feb;48(2):173-179. doi: 10.1111/vsu.13137. Epub 2018 Dec 20.

DOI:10.1111/vsu.13137

PMID:30569487

Abstract

OBJECTIVE

To evaluate a prototype dynamic laryngoplasty system (DLPS) in a static airflow model.

STUDY DESIGN

Experimental.

SAMPLE POPULATION

Ten equine larynges.

METHODS

The right arytenoid was fixed in abduction in all specimens. A left-sided laryngoplasty was performed with No. 2 Fiberwire and a FASTakII anchor. Each larynx was tested in a static airflow model. The system was adjusted to a flow rate of 55 L/s and prelaryngeal pressure of 12 mm Hg prior to testing in maximal arytenoid abduction. In phase 1, the left suture was loosened, shortened, and tested in 3-mm steps from 0 to 30 mm. In phase 2, the suture was tied with the DLPS in position at a target left-to-right quotient angle (LRQ) of 0.5. The DLPS was activated to target psi of 0, 25, and 50 for testing. Translaryngeal impedance (TLI), LRQ, cross-sectional areas (CSA), and resultant change in LRQ and CSA between, before, and during airflow testing were calculated.

RESULTS

In phase 1, TLI was reduced by suture shortening up to 6 mm (P = .001) but not by additional shortening (P > .05). In phase 2, activation of the DLPS reduced the TLI from 0 psi (0.43 ± 0.08 mm Hg/L/s) to 25 psi (0.16 ± 0.04 mm Hg/L/s, P < .001), but no further reduction was detected at maximal psi (P = .10).

CONCLUSION

Activation of the DLPS effectively reduced TLI.

CLINICAL SIGNIFICANCE

These results justify further investigation of the DLPS to assess its clinical applicability.

摘要

目的

在静态气流模型中评估一种原型动态喉成形术系统（DLPS）。

研究设计

实验性研究。

样本群体

10个马的喉部。

方法

在所有标本中，将右侧杓状软骨固定在外展位。使用2号纤维线和FASTakII锚进行左侧喉成形术。每个喉部在静态气流模型中进行测试。在最大杓状软骨外展测试前，将系统调整到流速为55升/秒和喉前压力为12毫米汞柱。在第1阶段，松开、缩短左侧缝线，并以3毫米的步长从0至30毫米进行测试。在第2阶段，将缝线与处于目标左右商角（LRQ）为0.5位置的DLPS系紧。激活DLPS使其达到目标磅力/平方英寸（psi）为0、25和50进行测试。计算跨喉阻抗（TLI）丶LRQ、横截面积（CSA）以及气流测试期间、之前和之间LRQ和CSA的结果变化。

结果

在第1阶段，缝线缩短至6毫米时TLI降低（P = 0.001），但进一步缩短则无此效果（P > 0.05）。在第2阶段，激活DLPS使TLI从0 psi（0.43±0.08毫米汞柱/升/秒）降至25 psi（0.16±0.04毫米汞柱/升/秒，P < 0.001），但在最大psi时未检测到进一步降低（P = 0.10）。