Yoshida Jun, Komoribayashi Nobukazu, Oikawa Kohki, Ohmama Shinichi, Kojima Daigo, Shimada Yasuyoshi, Ogasawara Kuniaki
Department of Neurosurgery, Iwate Medical University School of Medicine.
No Shinkei Geka. 2018 Dec;46(12):1081-1086. doi: 10.11477/mf.1436203872.
Early and late images of I-iomazenil(IMZ)single-photon emission computed tomography(SPECT)reflect distributions of cerebral blood flow and those of cortical benzodiazepine receptor binding potential, respectively. Crossed cerebellar diaschisis reflects left-to-right asymmetry of metabolism in the cerebral hemispheres. We present a case of a 67-year-old woman who developed transient aphasia 3 days after the onset of a mild acute subdural hematoma. Computed tomography scan and magnetic resonance imaging during aphasia did not show enlargement of the hematoma or any new lesions. Electroencephalography did not show any abnormalities. Early images of I-IMZ SPECT 3 days after the onset of aphasia revealed a decrease in radioactivity in the right cerebellar hemisphere relative to that in the left cerebellar hemisphere. Late images of the same I-IMZ SPECT displayed a decrease in radioactivity in the left cerebral hemisphere relative to that in the right cerebral hemisphere. Twenty-four days later, the aphasia disappeared and the left-to-right asymmetries of radioactivity in the cerebellar and cerebral hemispheres on the early and late I-IMZ SPECT images also resolved.
碘代异喹胍（IMZ）单光子发射计算机断层扫描（SPECT）的早期和晚期图像分别反映脑血流量分布和皮质苯二氮䓬受体结合潜能分布。交叉性小脑失联络反映了大脑半球代谢的左右不对称性。我们报告一例67岁女性，在轻度急性硬膜下血肿发病3天后出现短暂性失语。失语期间的计算机断层扫描和磁共振成像未显示血肿增大或任何新病灶。脑电图未显示任何异常。失语发病3天后的碘代异喹胍SPECT早期图像显示，右侧小脑半球放射性相对于左侧小脑半球降低。同一碘代异喹胍SPECT的晚期图像显示，左侧大脑半球放射性相对于右侧大脑半球降低。24天后，失语消失，碘代异喹胍SPECT早期和晚期图像中小脑和大脑半球放射性的左右不对称性也消失。
