a Department of Pharmacy Practice , University of Arkansas for Medical Sciences College of Pharmacy , Little Rock , Arkansas , USA.
Subst Use Misuse. 2019;54(2):331-339. doi: 10.1080/10826084.2018.1517175. Epub 2018 Dec 21.
The opioid epidemic in the United States is a problem that has developed over decades. While clinical, regulatory, and legislative changes have been implemented to combat this issue, changes will not be immediate. Moreover, the changes that have been carried out may have unintended negative consequences such as increased use of illicit opioids (e.g., heroin and synthetics) and challenges in effective and appropriate pain management.
This review focuses on the last three decades and presents key changes the United States has seen in the use of opioids. Conclusions/Importance: There have been numerous policy changes and programs aimed at decreasing opioid use and abuse in the United States; however, it will take a major shift in the mindset of clinicians, the general public, and policy makers to alleviate this epidemic.
美国的阿片类药物泛滥问题是一个历经数十年发展而来的问题。虽然已经实施了临床、监管和立法方面的变革来应对这一问题,但变革不会立竿见影。此外,已经开展的变革可能会带来意想不到的负面影响,例如非法阿片类药物(例如海洛因和合成药物)使用的增加,以及有效和适当的疼痛管理方面的挑战。
本综述重点关注过去三十年,介绍了美国在阿片类药物使用方面发生的主要变化。
结论/重要性:美国已经实施了多项旨在减少阿片类药物使用和滥用的政策变革和计划;然而,要缓解这一流行问题,还需要临床医生、公众和政策制定者的思维方式发生重大转变。