Moreno Romero J A, Pérez Muñoz N, Campoy Sánchez A, Urbano Carrillo M, Fernández Figueras M T
Servicio de Dermatología, Hospital Universitari General de Catalunya-Quirónsalud, Sant Cugat del Vallès, Barcelona, España.
Servicio de Anatomía Patológica, Hospital Universitari General de Catalunya-Quirónsalud, Sant Cugat del Vallès, Barcelona, España.
Actas Dermosifiliogr (Engl Ed). 2019 Apr;110(3):193-196. doi: 10.1016/j.ad.2018.09.012. Epub 2018 Dec 17.
Dermoscopy has improved diagnostic precision in the clinical evaluation of complex skin lesions by helping to pinpoint small clinically suspicious areas that are not visible to the naked eye but require histopathologic examination. Derm dotting is a new technique for selectively marking areas of interest to ensure they are examined under a microscope. Left unmarked, suspicious areas might not appear in routinely prepared cross sections or might be difficult to correlate with dermoscopic images. In vivo or ex vivo derm dotting involves the application of nail polish, which, unlike stains, leaves tissues unaltered. Dots can be placed by the dermatologist or laboratory staff during macroscopic preparation of the sample. Derm dotting is a simple, inexpensive technique that any dermatopathology laboratory can quickly adopt to improve diagnostic precision through better dermoscopic-histologic correlation.
皮肤镜检查通过帮助找出肉眼不可见但需要组织病理学检查的临床上可疑的小区域，提高了对复杂皮肤病变临床评估的诊断准确性。皮肤点涂是一种选择性标记感兴趣区域以确保在显微镜下进行检查的新技术。若不进行标记，可疑区域可能不会出现在常规制备的切片中，或者可能难以与皮肤镜图像相关联。体内或体外皮肤点涂涉及涂抹指甲油，与染色剂不同，指甲油不会改变组织。皮肤科医生或实验室工作人员可在样本的宏观制备过程中进行点涂。皮肤点涂是一种简单、廉价的技术，任何皮肤病理学实验室都可以迅速采用，通过更好的皮肤镜 - 组织学相关性来提高诊断准确性。
