D'Ortenzio Lori, Ribot Isabelle, Kahlon Bonnie, Bertrand Benoit, Bocaege Emmy, Raguin Emeline, Schattmann Annabelle, Brickley Megan
Department of Anthropology, McMaster University, Chester New Hall Rm. 517, 1280 Main Street West, Hamilton, Ontario L8S 4L9, Canada.
Facultés des arts et des sciences, Département d'Anthropologie Pavillon Lionel-Groulx, 3150, rue Jean Brillant, Bureau C-3068, Montreal, Quebec H3C 3J7, Canada.
Int J Paleopathol. 2018 Dec;23:32-42. doi: 10.1016/j.ijpp.2017.10.001. Epub 2017 Nov 7.
This study investigates morphological changes in pulp chambers of living and archaeological individuals with past vitamin D deficiency. Living individuals (n=29), four with detailed medical and dental records and three groups of archaeological individuals (n=25) were radiographed; selected individuals were further evaluated histologically for the presence of incremental interglobular dentin (IIGD), indicative of deficiency (28 living; 17 archaeological). Measurements of pulp horns/chambers from radiographs were conducted to quantify morphological observations. One group had clear skeletal evidence of rickets from St. Matthew, Quebec (n=1) and St. Jacques, France (n=4); a second group had slight skeletal indicators from Bastion des Ursulines, Quebec (n=6); and a third group lacked both skeletal and radiological evidence of deficiency from St. Antoine (n=6) and Pointe-aux-Trembles (n=4). Results showed archaeological individuals with clear and slight skeletal evidence of past deficiency displayed constricted or chair shaped pulp horns. Living individuals with deficiency exhibited similar pulp chamber morphology. Radiographic pulp horn/chamber measurements corroborated morphological findings and significant differences were found in pulp horn/chamber measurements between those with and without deficiency. Results suggest that radiograph assessment of teeth can be used as a screening technique to elucidate patterns of deficiency and select individuals for microCT or histological assessment.
本研究调查了过去存在维生素D缺乏的活体和考古个体牙髓腔的形态变化。对活体个体（n = 29）进行了X光检查，其中4人有详细的医学和牙科记录，另外三组考古个体（n = 25）也进行了X光检查；对选定个体进一步进行组织学评估，以确定是否存在指示维生素D缺乏的渐进性球间牙本质（IIGD）（28名活体个体；17名考古个体）。对X光片中的牙髓角/牙髓腔进行测量，以量化形态学观察结果。一组有来自魁北克圣马修（n = 1）和法国圣雅克（n = 4）的明显佝偻病骨骼证据；第二组有来自魁北克乌尔苏拉堡垒（n = 6）的轻微骨骼指标；第三组缺乏来自圣安托万（n = 6）和特伦布勒角（n = 4）的维生素D缺乏的骨骼和放射学证据。结果显示，有过去维生素D缺乏的明显和轻微骨骼证据的考古个体表现出牙髓角狭窄或呈椅形。有维生素D缺乏的活体个体表现出类似的牙髓腔形态。X光片上牙髓角/牙髓腔的测量结果证实了形态学发现，并且在有和没有维生素D缺乏的个体之间的牙髓角/牙髓腔测量中发现了显著差异。结果表明，牙齿的X光片评估可以用作一种筛查技术，以阐明维生素D缺乏模式，并选择个体进行显微CT或组织学评估。
