McLaren Rodney A, Atallah Fouad, Fisher Nelli, Minkoff Howard
Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, New York.
AJP Rep. 2018 Oct;8(4):e349-e354. doi: 10.1055/s-0038-1676297. Epub 2018 Nov 28.
This study was aimed to evaluate success rates of (1) external cephalic version (ECV) among women with one prior cesarean delivery (CD) and (2) maternal and neonatal outcomes after ECV among women with prior CD. Two linked studies using U.S. Natality Database were performed. First we performed a retrospective cohort comparing ECV success rates of women with prior CD and women without prior CD. Then we compared the outcomes of TOLACs (trial of labor after cesarean delivery) that occurred after ECV with those that occurred without ECV. Multivariable logistic regression analysis was used to estimate adverse outcomes. A total of 715 women had ECV after 36 weeks with prior CD and 9,976 had ECV without prior scar. ECV success rate with scar was 80.6% and without scar was 86.4% ( < 0.001). Seven hundred and sixteen women underwent TOLAC after ECV attempt and 234,617 underwent TOLAC without a preceding attempt. Women with preceding version had increased risks of maternal transfusion (1 vs. 0.4%, adjusted OR [odds ratio]: 2.48 [95% CI (confidence interval): 1.17-5.23]), unplanned hysterectomy (0.4 vs. 0.06%, adjusted OR: 6.90 [95% CI: 2.19-21.78]), and low 5-minute Apgar's score (2.5 vs. 1.5%, adjusted OR: 1.76 [95% CI: 1.10-2.82]). Women with prior CD may have a decrease in the rate of successful ECV. While the absolute risks are low, ECV appears to increase risks of adverse maternal and neonatal outcomes among women undergoing a trial of labor.
本研究旨在评估(1)有一次剖宫产史的女性进行外倒转术(ECV)的成功率,以及(2)有剖宫产史的女性进行ECV后的母婴结局。 使用美国出生数据库进行了两项关联研究。首先,我们进行了一项回顾性队列研究,比较有剖宫产史的女性和无剖宫产史的女性的ECV成功率。然后,我们比较了ECV后发生的剖宫产术后阴道试产(TOLAC)的结局与未进行ECV的TOLAC的结局。采用多变量逻辑回归分析来估计不良结局。 共有715名有剖宫产史的女性在孕36周后进行了ECV,9976名无剖宫产史的女性进行了ECV。有瘢痕者ECV成功率为80.6%,无瘢痕者为86.4%(<0.001)。716名女性在尝试ECV后进行了TOLAC,234617名女性未进行先行尝试就进行了TOLAC。先行外倒转术的女性发生母体输血的风险增加(1%对0.4%,调整后的比值比[OR]:2.48[95%置信区间(CI):1.17 - 5.23])、计划外子宫切除术(0.4%对0.06%,调整后的OR:6.90[95%CI:2.19 - 21.78])以及5分钟阿氏评分低的风险增加(2.5%对1.5%,调整后的OR:1.76[95%CI:1.10 - 2.82])。 有剖宫产史的女性进行ECV的成功率可能会降低。虽然绝对风险较低,但ECV似乎会增加进行阴道试产的女性发生不良母婴结局的风险。