Polat G
Department of Radiology, Medical Faculty, Ataturk University, Erzurum, Turkey.
Folia Morphol (Warsz). 2019;78(3):481-486. doi: 10.5603/FM.a2018.0116. Epub 2018 Dec 21.
The aim of the study was to evaluate middle cerebellar peduncle (MCP) asymmetry by diffusion tensor imaging (DTI) according to the dominant hand.
Sixty-four volunteers who met the exclusion and inclusion criteria were prospectively evaluated by DTI. Circular voxels of interest were drawn at the right and left MCP levels for all volunteers. The software automatically calculated the median values of fractional anisotropy (FA), mean diffusivity (MD), and number of fibres (NF). The volunteers were categorised as the right-handed (n = 44) and left-handed (n = 20) groups using the Dellatolas test. The mean values of FA, MD and NF were statistically compared between the two sides and the two groups.
In both groups, the mean value of FA for the right MCP was significantly higher than the left MCP (p = 0.0016 and p = 0.0032 for the right- and left-handed groups, respectively). In both groups, no significant difference was observed between the right and left MCPs in terms of MD and NF (p = 0.75, p = 0.69 and p = 0.96, p = 0.46, respectively). There was also no statistically significant difference between the groups for the mean values of FA, MD and NF of each MCP (p = 0.74, p = 0.26 and p = 0.26, respectively for the right MCP and p = 0.78, p = 0.37 and p = 0.54, respectively for the left MCP).
There is an asymmetry between the mean FA values of the right and left MCP. However, this asymmetry is independent of the dominant hand.
本研究旨在通过扩散张量成像（DTI）根据优势手评估小脑中脚（MCP）的不对称性。
对64名符合排除和纳入标准的志愿者进行前瞻性DTI评估。为所有志愿者在左右MCP水平绘制感兴趣的圆形体素。软件自动计算分数各向异性（FA）、平均扩散率（MD）和纤维数量（NF）的中位数。使用Dellatolas测试将志愿者分为右利手组（n = 44）和左利手组（n = 20）。对两侧和两组之间FA、MD和NF的平均值进行统计学比较。
在两组中，右侧MCP的FA平均值均显著高于左侧MCP（右利手组和左利手组分别为p = 0.0016和p = 0.0032）。在两组中，右侧和左侧MCP在MD和NF方面均未观察到显著差异（分别为p = 0.75、p = 0.69和p = 0.96、p = 0.46）。每组MCP的FA、MD和NF平均值在两组之间也无统计学显著差异（右侧MCP分别为p = 0.74、p = 0.26和p = 0.26，左侧MCP分别为p = 0.78、p = 0.37和p = 0.54）。
左右MCP的平均FA值之间存在不对称性。然而，这种不对称性与优势手无关。
