Boulot P, Deschamps F, Laffargue F, Viala J L
Centre de diagnostic anténatal, Centre Hospitalier Universitaire de Montpellier.
Rev Fr Gynecol Obstet. 1988 Jul-Sep;83(7-9):515-25.
The fetus and his environment which had remained, for so long, inaccessible to our exploratory techniques, is becoming every day, more and more accessible because of the various examinations now available. The biopsy of trophoblast which, after 10 weeks of amenorrhea, enable to obtain embryonic material and the tap of the umbilical chord under sonogram, permitting to obtain pure fetal blood after 18 weeks of amenorrhea, are an example of the new techniques which have completely modified the classical data of prenatal diagnosis. Now, the knowledge of parameters such as fetal haemostasis, immune status, metabolism and fetal karyotype, enabled the rapid development of fetal studies and already leads up to therapeutic procedures in utero.
胎儿及其环境长期以来一直处于我们探索技术难以触及的状态，但由于现有各种检查手段，如今越来越容易被了解。妊娠10周后进行的滋养层活检能够获取胚胎物质，在超声检查引导下妊娠18周后抽取脐带血可获得纯净胎儿血液，这些新技术彻底改变了产前诊断的传统数据。现在，对胎儿止血、免疫状态、代谢及胎儿核型等参数的了解，推动了胎儿研究的迅速发展，并且已经催生了子宫内治疗程序。
