Carstensen H, Pers C, Pryds O
Streptococcus Department, Statens Seruminstitut, Copenhagen, Denmark.
Scand J Infect Dis. 1988;20(4):407-10. doi: 10.3109/00365548809032476.
We present 2 cases of early onset group G streptococcal septicaemia in full term neonates, together with a review of 15 previously reported cases, including 3 late onset cases. Most likely the neonates were infected during passage through the birth canal or had been exposed in utero. In one neonate, meconium aspiration occurred, while in the other prolonged rupture of maternal membranes was a risk factor. Both responded well to treatment with benzylpenicillin and gentamicin. Among the 12 previously reported early onset cases, 5 (43%) had a fulminant course with complications such as progressive respiratory distress, shock, and disseminated intravascular coagulation.
我们报告了2例足月新生儿早发型G群链球菌败血症病例,并回顾了15例先前报告的病例,其中包括3例晚发型病例。最有可能的是,新生儿在通过产道时受到感染,或者在子宫内就已接触到病菌。其中1例新生儿发生了胎粪吸入,另1例产妇胎膜早破是危险因素。两者对苄星青霉素和庆大霉素治疗反应良好。在先前报告的12例早发型病例中,5例(43%)病情凶险,出现了进行性呼吸窘迫、休克和弥散性血管内凝血等并发症。